Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | ATR | Q13535 | 7/20 | 0.36 |
| ▸ | P2RX3 | P56373 | 6/20 | 0.36 |
| ▸ | P2RX2 | Q9UBL9 | 6/20 | 0.36 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.35 |
| ▸ | MTOR | P42345 | 2/20 | 0.35 |
| ▸ | IL1B | P01584 | 1/20 | 0.35 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.34 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.34 |
| ▸ | ATRIP | Q8WXE1 | 1/20 | 0.34 |
| ▸ | RICTOR | Q6R327 | 1/20 | 0.34 |
| ▸ | MAPKAP1 | Q9BPZ7 | 1/20 | 0.34 |
| ▸ | MLST8 | Q9BVC4 | 1/20 | 0.34 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.34 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25613109 | 0.86 | P2RX3 (0.36) | SLC6A4ATRP2RX3P2RX2CD274 | |
| SCHEMBL24005764 | 0.76 | PIK3CD (0.33) | SLC6A4CHEK1 | |
| SCHEMBL25613090 | 0.72 | GRM4 (0.39) | — | |
| SCHEMBL25613103 | 0.71 | CHRNA3 (0.42) | — | |
| SCHEMBL24005765 | 0.71 | LTA4H (0.48) | — | |
| SCHEMBL24005742 | 0.70 | CHRNB4 (0.46) | — | |
| SCHEMBL24005759 | 0.70 | FGFR1 (0.39) | — | |
| SCHEMBL19172448 | 0.70 | CHRNB2 (0.41) | P2RX3P2RX2ERBB2EPHA2 | |
| SCHEMBL24005751 | 0.70 | TTK (0.40) | — | |
| SCHEMBL25613114 | 0.70 | CHRNB4 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021223736-A1 | COMPOUNDS AS BCL-2 INHIBITORS | FOCHON PHARMACEUTICALS, LTD. (CN) | 2021-11-11 | — | — | WO | disclosed |