Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | XDH | P47989 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.32 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1841526 | 0.85 | MAPK1 (0.37) | KDM4EALDH1A1TDP1SMN1; SMN2CYP11B2 | |
| SCHEMBL10365692 | 0.77 | KDM4E (0.34) | KDM4EALDH1A1TDP1NR4A3SMN1; SMN2 | |
| SCHEMBL19780118 | 0.74 | ALDH1A1 (0.33) | KDM4EALDH1A1TDP1NR4A3SMN1; SMN2 | |
| SCHEMBL10890676 | 0.73 | RAB9A (0.49) | ALDH1A1TDP1NR4A3SMN1; SMN2TSHR | |
| SCHEMBL10720763 | 0.73 | ALDH1A1 (0.39) | KDM4EALDH1A1NR4A3SMN1; SMN2XDH | |
| SCHEMBL6963674 | 0.73 | POLB (0.55) | KDM4EALDH1A1NR4A3SMN1; SMN2XDH | |
| SCHEMBL966692 | 0.72 | KDM4E (0.41) | KDM4EALDH1A1TDP1NR4A3SMN1; SMN2 | |
| SCHEMBL7722135 | 0.72 | KDM4E (0.41) | KDM4EALDH1A1TDP1NR4A3SMN1; SMN2 | |
| SCHEMBL68535 | 0.72 | PDE10A (0.41) | KDM4EALDH1A1TDP1NR4A3SMN1; SMN2 | |
| SCHEMBL1663553 | 0.72 | SMN1; SMN2 (0.50) | KDM4EALDH1A1TDP1NR4A3SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250339569-A1 | CARBONIC ANHYDRASE IX LIGANDS | 3B PHARMACEUTICALS GMBH (DE) | 2025-11-06 | — | — | US | disclosed |
| WO-2023111350-A2 | CARBONIC ANHYDRASE IX LIGANDS | 3B PHARMACEUTICALS GMBH (DE) | 2023-06-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250339569-A1 | CARBONIC ANHYDRASE IX LIGANDS | CA9, CA13, CA4 | KDM4E 2877/4885ALDH1A1 4281/4885TDP1 4334/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.