Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 5/20 | 0.43 |
| ▸ | RAB9A | P51151 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.39 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.39 |
| ▸ | CHRNG | P07510 | 1/20 | 0.39 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29172164 | 0.82 | ALDH1A1 (0.42) | HPGDNPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL29090510 | 0.81 | CES2 (0.47) | HPGDNPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL2564307 | 0.80 | NPC1 (0.51) | HPGDNPC1RAB9ASMN1; SMN2MAPT | |
| Benzene SCHEMBL28160719 | 0.79 | NPC1 (0.49) | HPGDNPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL586754 | 0.79 | NPC1 (0.49) | HPGDNPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL29090508 | 0.79 | NPC1 (0.42) | HPGDNPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL3210075 | 0.77 | NPC1 (0.50) | HPGDNPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL15494373 | 0.71 | PARP1 (0.50) | FAAHHPGDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL28626730 | 0.70 | CYP19A1 (0.43) | HPGDNPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL2333379 | 0.70 | NPC1 (0.41) | HPGDNPC1RAB9ASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1890999-B1 | CYCLOAKYLIDENE- (ORTHO SUBSTITUTED PHENYL) -ACETONITRILES AND THEIR USE AS ODORANTS | GIVAUDAN SA (CH) | 2011-11-02 | — | — | EP | disclosed |
| US-7655701-B2 | Cycloalkylidene-(ortho substituted phenyl)-acetonitriles and their use as odorants | GIVAUDAN SA (CH) | 2010-02-02 | — | — | US | disclosed |
| US-20080200554-A1 | Cycloaklyldiene-(Ortho Substituted Phenyl)-Acetonitriles and Their Use as Odorants | GIVAUDAN SA (CH) | 2008-08-21 | — | — | US | disclosed |
| EP-1890999-A1 | CYCLOAKYLIDENE- (ORTHO SUBSTITUTED PHENYL) -ACETONITRILES AND THEIR USE AS ODORANTS | Givaudan SA (CH) | 2008-02-27 | — | — | EP | disclosed |
| WO-2006133592-A1 | CYCLOAKYLIDENE- (ORTHO SUBSTITUTED PHENYL) -ACETONITRILES AND THEIR USE AS ODORANTS | GIVAUDAN SA (CH) | 2006-12-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080200554-A1 | Cycloaklyldiene-(Ortho Substituted Phenyl)-Acetonitriles and Their Use as Odorants | OR10J3, OR51E2, OPRD1 | FAAH 423/4885HPGD 339/4885NPC1 2179/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.