Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.50 |
| ▸ | RAB9A | P51151 | 6/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.44 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL586754 | 0.98 | NPC1 (0.49) | NPC1RAB9AMAPTSMN1; SMN2CYP1A2 | |
| Benzene SCHEMBL28160719 | 0.98 | NPC1 (0.49) | NPC1RAB9AMAPTSMN1; SMN2CYP1A2 | |
| Phenylethyl Alcohol SCHEMBL28050164 | 0.84 | TDP1 (0.47) | NPC1RAB9AMAPTSMN1; SMN2CYP1A2 | |
| SCHEMBL1472474 | 0.82 | CHRNB2 (0.41) | NPC1RAB9AMAPTSMN1; SMN2CYP1A2 | |
| SCHEMBL2402920 | 0.82 | ALDH1A1 (0.46) | NPC1RAB9AMAPTSMN1; SMN2CYP1A2 | |
| SCHEMBL28626730 | 0.80 | CYP19A1 (0.43) | NPC1RAB9AMAPTSMN1; SMN2CYP1A2 | |
| SCHEMBL12320787 | 0.80 | CHRNB2 (0.45) | NPC1RAB9AMAPTSMN1; SMN2CYP1A2 | |
| SCHEMBL7602039 | 0.80 | SETD7 (0.61) | RAB9ACYP1A2CYP2C9CYP2C19CHRNB2 | |
| SCHEMBL29090498 | 0.79 | RAB9A (0.51) | NPC1RAB9AMAPTSMN1; SMN2CYP1A2 | |
| SCHEMBL31512564 | 0.79 | OGG1 (0.39) | NPC1RAB9AMAPTSMN1; SMN2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160346181-A1 | ORGANIC COMPOUNDS | GIVAUDAN SA (CH) | 2016-12-01 | — | — | US | claimed |
| EP-1968531-B1 | TOPICAL COMPOSITIONS FOR REDUCING SKIN IRRITATION | GIVAUDAN SA (CH) | 2014-12-31 | — | — | EP | claimed |
| CN-101262843-B | Improvements in or related to organic compounds | GIVAUDAN SA | 2013-01-30 | — | — | CN | claimed |
| US-20120184513-A1 | Organic Compounds | GIVAUDAN SA (CH) | 2012-07-19 | — | — | US | claimed |
| US-20100063011-A1 | Organic compounds | GIVAUDAN SA (CH) | 2010-03-11 | — | — | US | claimed |
| EP-1968531-A2 | TOPICAL COMPOSITIONS FOR REDUCING SKIN IRRITATION | Givaudan SA (CH) | 2008-09-17 | — | — | EP | claimed |
| CN-101262843-A | Improvements in or related to organic compounds | GIVAUDAN SA (CH) | 2008-09-10 | — | — | CN | claimed |
| WO-2007030961-A2 | TOPICAL COMPOSITIONS FOR REDUCING SKIN IRRITATION | GIVAUDAN SA (CH) | 2007-03-22 | — | — | WO | claimed |
| CN-116903494-A | Preparation method of alpha-alkyl nitrile derivative and alpha-alkenyl nitrile derivative | 浙江工业大学 | 2023-10-20 | — | — | CN | disclosed |
| CN-109415306-A | The preparation method of 2- cyclohexylidene -2- phenylacetonitrile and its odorous analogue | 阿甘香气及精细化学有限公司 | 2019-03-01 | — | — | CN | disclosed |
| US-20160346181-A1 | ORGANIC COMPOUNDS | GIVAUDAN SA (CH) | 2016-12-01 | — | — | US | disclosed |
| US-9440097-B2 | Organic compounds | GIVAUDAN SA (CH) | 2016-09-13 | — | — | US | disclosed |
| EP-1968531-B1 | TOPICAL COMPOSITIONS FOR REDUCING SKIN IRRITATION | GIVAUDAN SA (CH) | 2014-12-31 | — | — | EP | disclosed |
| CN-101262843-B | Improvements in or related to organic compounds | GIVAUDAN SA | 2013-01-30 | — | — | CN | disclosed |
| US-7390772-B2 | 1-phenyl-spiro[2.5]octane-1-carbonitrile analogues their use in fragrance formulations | INTERNATIONAL FLAVOR & FRAGRANCES INC. (US) | 2008-06-24 | — | — | US | disclosed |
| US-20070270328-A1 | 1-PHENYL-SPIRO[2.5]OCTANE-1-CARBONITRILE ANALOGUES THEIR USE IN FRAGRANCE FORMULATIONS | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2007-11-22 | — | — | US | disclosed |
| US-20070270328-A1 | 1-PHENYL-SPIRO[2.5]OCTANE-1-CARBONITRILE ANALOGUES THEIR USE IN FRAGRANCE FORMULATIONS | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2007-11-22 | — | — | US | disclosed |
| US-20070270328-A1 | 1-PHENYL-SPIRO[2.5]OCTANE-1-CARBONITRILE ANALOGUES THEIR USE IN FRAGRANCE FORMULATIONS | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2007-11-22 | — | — | US | disclosed |
| EP-1857437-A1 | 1-Phenyl-spiro[2.5]octane-1-carbonitrile analogues and their use in fragrance formulations | INTERNATIONAL FLAVORS & FRAGRANCES, INC. (US) | 2007-11-21 | — | — | EP | disclosed |
| WO-2007030961-A2 | TOPICAL COMPOSITIONS FOR REDUCING SKIN IRRITATION | GIVAUDAN SA (CH) | 2007-03-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100063011-A1 | Organic compounds | CYP1A1, CYP1B1, OXER1 | NPC1 1743/4885RAB9A 4769/4885MAPT 3556/4885 |
| US-20120184513-A1 | Organic Compounds | CYP1A1, CYP1B1, OXER1 | NPC1 1743/4885RAB9A 4769/4885MAPT 3556/4885 |
| US-20160346181-A1 | ORGANIC COMPOUNDS | CYP1A1, CYP1B1, OXER1 | NPC1 1743/4885RAB9A 4769/4885MAPT 3556/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.