Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 4/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14682740 | 0.88 | SLC6A4 (0.34) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL2557929 | 0.84 | SMN1; SMN2 (0.34) | SLC6A4SLC6A2SLC6A3SMN1; SMN2 | |
| SCHEMBL437166 | 0.79 | SLC6A2 (0.32) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL6326457 | 0.79 | SMN1; SMN2 (0.41) | SLC6A4SLC6A2SLC6A3SMN1; SMN2 | |
| SCHEMBL10098727 | 0.76 | — | — | |
| SCHEMBL6982116 | 0.73 | TDP1 (0.40) | SMN1; SMN2 | |
| SCHEMBL13227173 | 0.73 | ADRA2A (0.42) | — | |
| SCHEMBL13273127 | 0.73 | SMN1; SMN2 (0.36) | SLC6A4SLC6A2SLC6A3SMN1; SMN2 | |
| SCHEMBL2561571 | 0.73 | CACNG8 (0.40) | SLC6A4SLC6A2SLC6A3SMN1; SMN2 | |
| SCHEMBL14682733 | 0.71 | MAP3K14 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2560960-B1 | PROCESS FOR THE PREPARATION OF PYRAZOLE CARBOXYLIC ACID AMIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2014-02-26 | — | — | EP | disclosed |
| US-8524915-B2 | Process for the preparation of pyrazole carboxylic acid amides | SYNGENTA CROP PROTECTION LLC (US) | 2013-09-03 | — | — | US | disclosed |
| US-8524915-B2 | Process for the preparation of pyrazole carboxylic acid amides | SYNGENTA CROP PROTECTION LLC (US) | 2013-09-03 | — | — | US | disclosed |
| EP-2560960-A1 | PROCESS FOR THE PREPARATION OF PYRAZOLE CARBOXYLIC ACID AMIDES | Syngenta Participations AG (CH) | 2013-02-27 | — | — | EP | disclosed |
| US-20130041160-A1 | PROCESS FOR THE PREPARATION OF PYRAZOLE CARBOXYLIC ACID AMIDES | SYNGENTA CROP PROTECTION LLC (US) | 2013-02-14 | — | — | US | disclosed |
| US-20130041160-A1 | PROCESS FOR THE PREPARATION OF PYRAZOLE CARBOXYLIC ACID AMIDES | SYNGENTA CROP PROTECTION LLC (US) | 2013-02-14 | — | — | US | disclosed |
| WO-2011131544-A1 | PROCESS FOR THE PREPARATION OF PYRAZOLE CARBOXYLIC ACID AMIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2011-10-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130041160-A1 | PROCESS FOR THE PREPARATION OF PYRAZOLE CARBOXYLIC ACID AMIDES | CBR3, F12, CBR1 | SLC6A4 3069/4885SLC6A2 4585/4885SLC6A3 3440/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.