Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | ERN1 | O75460 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9269601 | 0.89 | TDP1 (0.38) | TDP1GPR35SMN1; SMN2TSHRERN1 | |
| SCHEMBL14977883 | 0.89 | TDP1 (0.38) | TDP1GPR35SMN1; SMN2TSHRERN1 | |
| SCHEMBL12446428 | 0.87 | GPR35 (0.44) | TDP1GPR35SMN1; SMN2TSHRERN1 | |
| SCHEMBL4572413 | 0.87 | GPR35 (0.41) | TDP1GPR35SMN1; SMN2TSHRERN1 | |
| SCHEMBL4572414 | 0.85 | GPR35 (0.40) | TDP1GPR35SMN1; SMN2TSHRERN1 | |
| SCHEMBL4572403 | 0.85 | GPR35 (0.40) | TDP1GPR35SMN1; SMN2TP53TSHR | |
| SCHEMBL6979277 | 0.85 | GPR35 (0.40) | TDP1GPR35SMN1; SMN2TP53TSHR | |
| SCHEMBL4572411 | 0.85 | TDP1 (0.37) | TDP1GPR35SMN1; SMN2TP53TSHR | |
| SCHEMBL12677202 | 0.83 | GPR35 (0.38) | TDP1GPR35SMN1; SMN2TP53TSHR | |
| SCHEMBL4572402 | 0.78 | TDP1 (0.41) | TDP1GPR35SMN1; SMN2TP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11647749-B2 | Fungicidal compositions | SYNGENTA PARTICIPATIONS AG (CH) | 2023-05-16 | — | — | US | disclosed |
| US-9878970-B1 | Process for the preparation of benzonorbornenes | SYNGENTA CROP PROTECTION, LLC (US) | 2018-01-30 | — | — | US | disclosed |
| US-20180016211-A1 | PROCESS FOR THE PREPARATION OF BENZONORBORNENES | SYNGENTA CROP PROTECTION, LLC (US) | 2018-01-18 | — | — | US | disclosed |
| US-9796646-B2 | Process for the preparation of benzonorbornenes | SYNGENTA CROP PROTECTION, LLC (US) | 2017-10-24 | — | — | US | disclosed |
| US-20170202220-A1 | FUNGICIDAL COMPOSITIONS | SYNGENTA CROP PROTECTION, LLC (US) | 2017-07-20 | — | — | US | disclosed |
| US-9642365-B2 | Fungicidal compositions | SYNGENTA CROP PROTECTION, LLC (US) | 2017-05-09 | — | — | US | disclosed |
| US-20160192655-A1 | FUNGICIDAL COMPOSITIONS | SYNGENTA CROP PROTECTION, LLC (US) | 2016-07-07 | — | — | US | disclosed |
| US-9314022-B2 | Fungicidal compositions | SYNGENTA CROP PROTECTION, LLC (US) | 2016-04-19 | — | — | US | disclosed |
| US-9115043-B2 | Process for the preparation of benzonorbornenes | SYNGENTA CROP PROTECTION, LLC (US) | 2015-08-25 | — | — | US | disclosed |
| US-20150141712-A1 | PROCESS FOR THE PREPARATION OF BENZONORBORNENES | SYNGENTA PARTICIPATIONS AG (CH) | 2015-05-21 | — | — | US | disclosed |
| US-20110207958-A1 | PROCESS FOR THE PREPARATION OF BENZONORGORNENES | SYNGENTA CROP PROTECTION LLC (US) | 2011-08-25 | — | — | US | disclosed |
| US-20100216640-A1 | FUNGICIDAL COMPOSITIONS | SYNGENTA CROP PROTECTION, INC. (US) | 2010-08-26 | — | — | US | disclosed |
| US-20100204482-A1 | HETEROCYCLIC AMIDE DERIVATIVES USEFUL AS MICROBIOCIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2010-08-12 | — | — | US | disclosed |
| US-20100204482-A1 | HETEROCYCLIC AMIDE DERIVATIVES USEFUL AS MICROBIOCIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2010-08-12 | — | — | US | disclosed |
| US-20100204287-A1 | HETEROCYCLIC AMIDE DERIVATIVES USEFUL AS MICROBIOCIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2010-08-12 | — | — | US | disclosed |
| US-7732469-B2 | for controlling or preventing infestation of plants by phytopathogenic microorganisms, preferably fungi | SYNGENTA CROP PROTECTION, INC. (US) | 2010-06-08 | — | — | US | disclosed |
| US-7732469-B2 | for controlling or preventing infestation of plants by phytopathogenic microorganisms, preferably fungi | SYNGENTA CROP PROTECTION, INC. (US) | 2010-06-08 | — | — | US | disclosed |
| US-20080227835-A1 | Heterocyclic Amide Derivatives Useful as Microbiocides | SYNGENTA CROP PROTECTION, INC. (US) | 2008-09-18 | — | — | US | disclosed |
| US-20080227835-A1 | Heterocyclic Amide Derivatives Useful as Microbiocides | SYNGENTA CROP PROTECTION, INC. (US) | 2008-09-18 | — | — | US | disclosed |
| WO-2007048556-A1 | HETEROCYCLIC AMIDE DERIVATIVES USEFUL AS MICROBIOCIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2007-05-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11647749-B2 | Fungicidal compositions | BROX, RER1, BLVRB | TDP1 1537/4885GPR35 3687/4885SMN1; SMN2 2686/4885 |
| US-20150141712-A1 | PROCESS FOR THE PREPARATION OF BENZONORBORNENES | CCL5, CXCR2, CXCR3 | TDP1 3441/4885GPR35 3913/4885SMN1; SMN2 4720/4885 |
| US-20100204482-A1 | HETEROCYCLIC AMIDE DERIVATIVES USEFUL AS MICROBIOCIDES | CBR3, CBR1, CYP8B1 | TDP1 3661/4885GPR35 4032/4885SMN1; SMN2 4736/4885 |
| US-20160192655-A1 | FUNGICIDAL COMPOSITIONS | BROX, RER1, BLVRB | TDP1 1537/4885GPR35 3687/4885SMN1; SMN2 2686/4885 |
| US-20100216640-A1 | FUNGICIDAL COMPOSITIONS | BROX, RER1, BLVRB | TDP1 1545/4885GPR35 3642/4885SMN1; SMN2 2476/4885 |
| US-20180016211-A1 | PROCESS FOR THE PREPARATION OF BENZONORBORNENES | CCL5, CXCR2, CXCR3 | TDP1 3639/4885GPR35 3512/4885SMN1; SMN2 4731/4885 |
| US-20170202220-A1 | FUNGICIDAL COMPOSITIONS | BROX, RER1, BLVRB | TDP1 1537/4885GPR35 3687/4885SMN1; SMN2 2686/4885 |
| US-20100204287-A1 | HETEROCYCLIC AMIDE DERIVATIVES USEFUL AS MICROBIOCIDES | CBR3, CBR1, CYP8B1 | TDP1 3379/4885GPR35 3868/4885SMN1; SMN2 4724/4885 |
| US-20110207958-A1 | PROCESS FOR THE PREPARATION OF BENZONORGORNENES | CBR1, CBR3, CYC1 | TDP1 3399/4885GPR35 3286/4885SMN1; SMN2 4448/4885 |
| US-20080227835-A1 | Heterocyclic Amide Derivatives Useful as Microbiocides | CBR3, CBR1, CYP8B1 | TDP1 3870/4885GPR35 3375/4885SMN1; SMN2 4777/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.