Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.53 |
| ▸ | MAOA | P21397 | 3/20 | 0.53 |
| ▸ | PRKCI | P41743 | 1/20 | 0.53 |
| ▸ | MIF | P14174 | 6/20 | 0.44 |
| ▸ | CYP26A1 | O43174 | 2/20 | 0.44 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.43 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.39 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2561343 | 0.85 | PBRM1 (0.56) | MAOBMAOAPRKCIPBRM1AKR1B1 | |
| SCHEMBL6196729 | 0.81 | MAOB (0.47) | MAOBMAOAPRKCIMIFCYP26A1 | |
| SCHEMBL784291 | 0.73 | MAOB (0.59) | MAOBMAOAPRKCIMIFCYP26A1 | |
| SCHEMBL7472016 | 0.72 | DRD2 (0.39) | MAOBMAOAPRKCIPBRM1ESR2 | |
| SCHEMBL389710 | 0.72 | MAOB (0.78) | MAOBMAOAPRKCIMIFCYP26A1 | |
| SCHEMBL910775 | 0.72 | CES1 (0.52) | MAOBMAOAMIF | |
| SCHEMBL23142696 | 0.71 | MAOB (0.58) | MAOBMAOAPRKCIMIFCYP26A1 | |
| SCHEMBL228128 | 0.69 | MAOA (1.00) | MAOBMAOAPRKCIMIFCYP26A1 | |
| SCHEMBL3825921 | 0.69 | MAOA (0.92) | MAOBMAOAPRKCIMIFCYP26A1 | |
| SCHEMBL6198766 | 0.69 | PBRM1 (0.50) | MAOBMAOAPRKCIPBRM1HSD17B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2194035-B1 | Hydroxytetralones | SALTIGO GMBH (DE) | 2011-11-02 | — | — | EP | claimed |