SCHEMBL389710

SCHEMBL389710

O=C1CCc2cc(O)ccc21

nearest known ligand 0.78

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MAOB P27338 3/20 0.78
MAOA P21397 2/20 0.78
PRKCI P41743 1/20 0.78
HSD17B1 P14061 4/20 0.72
PBRM1 Q86U86 1/20 0.70
CASP1 P29466 1/20 0.59
CASP7 P55210 1/20 0.59
HSD17B10 Q99714 1/20 0.59
MIF P14174 5/20 0.53
CYP26A1 O43174 1/20 0.53
AKR1B1 P15121 1/20 0.51
GRM5 P41594 1/20 0.49
HSP90AA1 P07900 1/20 0.49
CYP19A1 P11511 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL228128 0.88 MAOA (1.00) MAOBMAOAPRKCIHSD17B1PBRM1
SCHEMBL3825921 0.88 MAOA (0.92) MAOBMAOAPRKCIHSD17B1PBRM1
SCHEMBL5203864 0.85 MAOB (0.69) MAOBMAOAPRKCIHSD17B1PBRM1
SCHEMBL9827282 0.85 MAOB (0.58) MAOBMAOAPRKCIHSD17B1PBRM1
SCHEMBL1030949 0.84 HSD17B1 (1.00) MAOBMAOAPRKCIHSD17B1PBRM1
SCHEMBL784291 0.84 MAOB (0.59) MAOBMAOAPRKCIHSD17B1PBRM1
SCHEMBL28880 0.83 PBRM1 (1.00) MAOBMAOAPRKCIHSD17B1PBRM1
SCHEMBL30137886 0.83 PBRM1 (1.00) MAOBMAOAPRKCIHSD17B1PBRM1
SCHEMBL6200904 0.81 MAOB (0.54) MAOBMAOAPRKCIHSD17B1PBRM1
SCHEMBL23142696 0.81 MAOB (0.58) MAOBMAOAPRKCIHSD17B1PBRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 660 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250075147-A1 FRAGRANCE AND FLAVOR COMPOSITIONS COMPRISING NEW FLAVOR AND FRAGRANCE INGREDIENTS OSMO LABS, PBC 2025-03-06 US claimed
CN-117757175-A flame-retardant polymer composition for new energy vehicle and production process thereof 河南云瀚实业有限公司 2024-03-26 CN claimed
CN-114436995-B Morpholine-indenone-chalcone derivative fluorescent probe and preparation method and application thereof 河南理工大学 2023-04-25 CN claimed
CN-111171809-B Hydroxyl indenone derivative fluorescent probe and preparation method and application thereof 广州大学 2022-12-27 CN claimed
CN-114436995-A Morpholine-indanone-chalcone derivative fluorescent probe and preparation method and application thereof 河南理工大学 2022-05-06 CN claimed
CN-108558627-B Method for preparing 5-hydroxy-1-indanone 山西大学 2020-09-29 CN claimed
CN-111171809-A Hydroxyl indenone derivative fluorescent probe and preparation method and application thereof 广州大学 2020-05-19 CN claimed
US-10092786-B2 Fire extinguishing composition comprising aldoketones compound XI'AN WESTPEACE FIRE TECHNOLOGY CO., LTD. (CN) 2018-10-09 US claimed
US-20160332016-A1 Fire Extinguishing Composition Comprising Aldoketones Compound NANO FIRE, LLC 2016-11-17 US claimed
US-20260146026-A1 COMPOUND, COMPOSITION, CURED PRODUCT, METHOD FOR PRODUCING CURED PRODUCT, AND METHOD FOR PRODUCING ELECTRONIC COMPONENT ADEKA CORPORATION (JP) 2026-05-28 US disclosed
US-20260079084-A1 COMPOUND, EXTRACELLULAR VESICLE STAINING AGENT, AND FLUORESCENT STAINING METHOD FOR EXTRACELLULAR VESICLES NATIONAL UNIV CORPORATION TOKAI NATIONAL HIGHER EDUCATION AND RESEARCH SYSTEM (JP) 2026-03-19 US disclosed
US-20260022094-A1 Compounds for the Treatment of Neurodegenerative Diseases CELGENE CORPORATION (US) 2026-01-22 US disclosed
US-20260001846-A1 SPIROCYCLOHEXANE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USES AS ANTI-APOPTOTIC INHIBITORS SERVIER LAB (FR) 2026-01-01 US disclosed
EP-4610254-A1 COMPOUND, COMPOSITION, CURED PRODUCT, METHOD FOR PRODUCING CURED PRODUCT, AND METHOD FOR PRODUCING ELECTRONIC COMPONENT ADEKA CORPORATION (JP) 2025-09-03 EP disclosed
US-4291050-A DIURETICS, ANTIEDEMIC AGENTS, HYPOTENSIVE AGENTS MERCK & CO., INC. (US) 1981-09-22 US disclosed
US-4291168-A DIURETICS MEAD JOHNSON & COMPANY (US) 1981-09-22 US disclosed
US-4247715-A BIURETICS MEAD JOHNSON & COMPANY (US) 1981-01-27 US disclosed
US-4247715-A BIURETICS MEAD JOHNSON & COMPANY (US) 1981-01-27 US disclosed
US-4109088-A ANTIDEPRESSANTS YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) 1978-08-22 US disclosed
US-3931239-A DIURETIC, HYPOTENSIVE MERCK & CO., INC. (US) 1976-01-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260001846-A1 SPIROCYCLOHEXANE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USES AS ANTI-APOPTOTIC INHIBITORS BCL2, BCL2A1, BAX MAOB 3576/4885MAOA 3647/4885PRKCI 1088/4885
US-20260079084-A1 COMPOUND, EXTRACELLULAR VESICLE STAINING AGENT, AND FLUORESCENT STAINING METHOD FOR EXTRACELLULAR VESICLES EXOSC4, CHMP4B, EXOSC5 MAOB 2135/4885MAOA 2773/4885PRKCI 4201/4885
US-20260146026-A1 COMPOUND, COMPOSITION, CURED PRODUCT, METHOD FOR PRODUCING CURED PRODUCT, AND METHOD FOR PRODUCING ELECTRONIC COMPONENT CBR3, CBR1, NOTUM MAOB 878/4885MAOA 959/4885PRKCI 3265/4885
US-20260022094-A1 Compounds for the Treatment of Neurodegenerative Diseases S1PR5, CLN6, S1PR1 MAOB 1817/4885MAOA 1702/4885PRKCI 1711/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.