SCHEMBL2563486

SCHEMBL2563486

Nc1ccc(-c2cc3ccccc3[nH]2)c(N)c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDR P35968 4/20 0.53
CHEK1 O14757 1/20 0.53
RAB9A P51151 5/20 0.50
NPC1 O15118 4/20 0.50
KDM4E B2RXH2 5/20 0.49
MAPT P10636 5/20 0.49
ALDH1A1 P00352 5/20 0.49
MEN1 O00255 4/20 0.49
HPGD P15428 4/20 0.49
KMT2A Q03164 4/20 0.49
SMN1; SMN2 Q16637 2/20 0.49
NPSR1 Q6W5P4 1/20 0.49
AOC3 Q16853 2/20 0.48
HSD17B10 Q99714 3/20 0.46
USP2 O75604 1/20 0.46
LMNA P02545 1/20 0.46
POLB P06746 1/20 0.46
GAA P10253 1/20 0.46
ALOX15 P16050 1/20 0.46
TDP1 Q9NUW8 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29733654 1.00 KDR (0.53) KDRCHEK1RAB9ANPC1KDM4E
SCHEMBL29419326 1.00 KDR (0.53) KDRCHEK1RAB9ANPC1KDM4E
Hydrochloric Acid SCHEMBL31035997 0.98 KDR (0.51) KDRCHEK1RAB9ANPC1KDM4E
Hydrochloric Acid SCHEMBL3675763 0.98 KDR (0.51) KDRCHEK1RAB9ANPC1KDM4E
Hydrochloric Acid SCHEMBL5683292 0.98 KDR (0.51) KDRCHEK1RAB9ANPC1KDM4E
SCHEMBL8965829 0.85 RAB9A (0.58) KDRCHEK1RAB9ANPC1KDM4E
SCHEMBL221259 0.84 KDR (0.58) KDRCHEK1RAB9ANPC1KDM4E
SCHEMBL29361867 0.84 KDR (0.58) KDRCHEK1RAB9ANPC1KDM4E
SCHEMBL9469591 0.83 RAB9A (0.58) KDRCHEK1RAB9ANPC1KDM4E
SCHEMBL9469103 0.80 KDR (0.46) KDRCHEK1RAB9ANPC1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 217 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116482379-A Method, application, device, computer device and storage medium for diagnosing sperm conventional in vitro fertilization results 中信湘雅生殖与遗传专科医院有限公司 2023-07-25 CN claimed
EP-1549949-B1 METHOD FOR DETECTING AND LIMITING BREAST CARCINOMA RISK BY A MICRONUCLEUS TEST OF BINUCLEAR CELLS VOGEL WALTER (DE) 2010-02-17 EP claimed
EP-0599337-B1 Method for detection of nucleic acid and probe therefor CANON KK (JP) 2006-03-08 EP claimed
EP-1549949-A2 METHOD FOR DETECTING AND LIMITING BREAST CARCINOMA RISK BY A MICRONUCLEUS TEST OF BINUCLEAR CELLS Vogel, Walter (DE) 2005-07-06 EP claimed
WO-2004034055-A2 METHOD FOR DETECTING AND LIMITING BREAST CARCINOMA RISK BY A MICRONUCLEUS TEST OF BINUCLEAR CELLS VOGEL WALTHER (DE) 2004-04-22 WO claimed
WO-2002014859-A1 MICRONUCLEUS ASSAY DIATECH PTY LTD (AU) 2002-02-21 WO claimed
US-20260115323-A1 METHOD FOR TREATING X-LINKED RETINOSCHISIS TAIPEI VETERANS GENERAL HOSPITAL (TW) 2026-04-30 US disclosed
US-12533350-B2 Use of melanocortin-1 receptor agonist Tanabe Pharma Corporation (JP) 2026-01-27 US disclosed
US-20250381174-A1 NOVEL USE OF MELANOCORTIN-1 RECEPTOR AGONIST MITSUBISHI TANABE PHARMA CORPORATION (JP) 2025-12-18 US disclosed
EP-4603586-A1 INHIBITORY OLIGONUCLEOTIDES AGAINST ADAMTS7 Universität zu Lübeck (DE) 2025-08-20 EP disclosed
US-20250134879-A1 NOVEL USE OF MELANOCORTIN-1 RECEPTOR AGONIST MITSUBISHI TANABE PHARMA CORPORATION (JP) 2025-05-01 US disclosed
US-12214026-B2 Vaccine for falciparum malaria RHODE ISLAND HOSPITAL (US) 2025-02-04 US disclosed
EP-4473967-A1 NOVEL USE OF MELANOCORTIN-1 RECEPTOR AGONIST Mitsubishi Tanabe Pharma Corporation (JP) 2024-12-11 EP disclosed
EP-1103609-A1 DIFFERENTIATION REGULATORY FACTOR EXPRESSED SPECIFICALLY IN TESTIS Chugai Research Institute for Molecular Medicine Inc. (JP) 2001-05-30 EP disclosed
WO-2001029062-A2 METHOD FOR MODULATION OF CELL PHENOTYPE UNIVERSITY TECHNOLOGY CORPORATION (US) 2001-04-26 WO disclosed
EP-1007072-A1 GLIAL CELL LINE-DERIVED NEUROTROPHIC FACTOR RECEPTORS CEPHALON, INC. (US) 2000-06-14 EP disclosed
EP-1004665-A1 SCAVENGER RECEPTOR-LIKE PROTEINS JAPAN TOBACCO INC. (JP) 2000-05-31 EP disclosed
WO-1998052591-A1 GLIAL CELL LINE-DERIVED NEUROTROPHIC FACTOR RECEPTORS CEPHALON INC. (US) 1998-11-26 WO disclosed
US-5620689-A ADMINISTERING A SUSPENSION OF LIPOSOMES HAVING A SURFACE COATING OF POLYETHYLENE GLYCOL CHAINS SEQUUS PHARMACEUUTICALS, INC. (US) 1997-04-15 US disclosed
EP-0519866-A1 Novel anti-HIV antibodies CIBA-GEIGY AG (CH) 1992-12-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12533350-B2 Use of melanocortin-1 receptor agonist MC1R, CMKLR1, MC3R KDR 475/4885CHEK1 4238/4885RAB9A 2725/4885
US-20260115323-A1 METHOD FOR TREATING X-LINKED RETINOSCHISIS XBP1, EIF2AK4, RPS6KB2 KDR 2594/4885CHEK1 3047/4885RAB9A 149/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.