Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 9/20 | 0.46 |
| ▸ | KDM4C | Q9H3R0 | 9/20 | 0.46 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | KDM5C | P41229 | 1/20 | 0.35 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.35 |
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.34 |
| ▸ | KDM4A | O75164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18195632 | 0.95 | KDM5A (0.40) | KDM5AKDM4CDNM1EPHX2HDAC1 | |
| SCHEMBL2607007 | 0.87 | MEN1 (0.45) | KDM5AKDM4CDNM1EPHX2HDAC1 | |
| SCHEMBL25634871 | 0.84 | PAOX (0.41) | KDM5AKDM4CDNM1EPHX2HDAC1 | |
| SCHEMBL20674797 | 0.83 | DNM1 (0.44) | KDM5AKDM4CDNM1EPHX2HDAC1 | |
| SCHEMBL14060671 | 0.83 | DNM1 (0.50) | KDM5AKDM4CDNM1KDM5CKDM5B | |
| SCHEMBL12662980 | 0.82 | KDM5A (0.41) | KDM5AKDM4CDNM1EPHX2KDM5C | |
| SCHEMBL25495940 | 0.81 | DNM1 (0.47) | KDM5AKDM4CDNM1EPHX2HDAC1 | |
| SCHEMBL30073985 | 0.81 | DNM1 (0.47) | KDM5AKDM4CDNM1EPHX2HDAC1 | |
| SCHEMBL134923 | 0.80 | EPHX2 (0.46) | EPHX2HDAC1HDAC2HDAC6HDAC8 | |
| SCHEMBL14482131 | 0.78 | EPHX2 (0.49) | EPHX2HDAC1HDAC2HDAC6HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230372537-A1 | LIPID NANOPARTICLE FORMULATIONS | ACUITAS THERAPEUTICS INC (CA) | 2023-11-23 | — | — | US | disclosed |
| US-11771715-B2 | Circular RNA compositions and methods | ORNA THERAPEUTICS, INC. (US) | 2023-10-03 | — | — | US | disclosed |
| US-11766449-B2 | Circular RNA compositions and methods | ORNA THERAPEUTICS, INC. (US) | 2023-09-26 | — | — | US | disclosed |
| US-11712481-B2 | Lipid nanoparticle formulations | Acuitas Therapeutics, Inc. (CA) | 2023-08-01 | — | — | US | disclosed |
| US-20230226096-A1 | CIRCULAR RNA COMPOSITIONS AND METHODS | ORNA THERAPEUTICS, INC. | 2023-07-20 | — | — | US | disclosed |
| US-11679120-B2 | Circular RNA compositions and methods | ORNA THERAPEUTICS, INC. (US) | 2023-06-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11712481-B2 | Lipid nanoparticle formulations | LIPA, PLIN3, PLIN1 | KDM5A 4478/4885KDM4C 4541/4885DNM1 688/4885 |
| US-20230372537-A1 | LIPID NANOPARTICLE FORMULATIONS | LIPA, PLIN3, PLIN1 | KDM5A 4478/4885KDM4C 4541/4885DNM1 688/4885 |
| US-11771715-B2 | Circular RNA compositions and methods | RTCB, HNRNPA1, HNRNPAB | KDM5A 4656/4885KDM4C 4245/4885DNM1 4456/4885 |
| US-20230226096-A1 | CIRCULAR RNA COMPOSITIONS AND METHODS | RTCB, HNRNPA1, HNRNPAB | KDM5A 4656/4885KDM4C 4245/4885DNM1 4456/4885 |
| US-11679120-B2 | Circular RNA compositions and methods | RTCB, HNRNPA1, HNRNPAB | KDM5A 4656/4885KDM4C 4245/4885DNM1 4456/4885 |
| US-11766449-B2 | Circular RNA compositions and methods | RTCB, RNGTT, HNRNPAB | KDM5A 4646/4885KDM4C 4235/4885DNM1 4429/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.