Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 12/20 | 0.94 |
| ▸ | HTT | P42858 | 2/20 | 0.94 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.79 |
| ▸ | RAD52 | P43351 | 2/20 | 0.79 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.67 |
| ▸ | TP53 | P04637 | 1/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.67 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.67 |
| ▸ | TSHR | P16473 | 1/20 | 0.67 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.67 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.67 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.64 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL18334663 | 1.00 | DNM1 (0.94) | DNM1HTTHSP90AA1RAD52KMT2A | |
| Bromide SCHEMBL8071608 | 1.00 | DNM1 (0.94) | DNM1HTTHSP90AA1RAD52KMT2A | |
| Bromide SCHEMBL10855468 | 1.00 | DNM1 (0.94) | DNM1HTTHSP90AA1RAD52KMT2A | |
| Bromide SCHEMBL18141261 | 1.00 | DNM1 (0.94) | DNM1HTTHSP90AA1RAD52KMT2A | |
| Bromide SCHEMBL5490891 | 1.00 | DNM1 (0.94) | DNM1HTTHSP90AA1RAD52KMT2A | |
| Bromide SCHEMBL11340296 | 1.00 | DNM1 (0.94) | DNM1HTTHSP90AA1RAD52KMT2A | |
| Bromide SCHEMBL8110085 | 1.00 | DNM1 (0.94) | DNM1HTTHSP90AA1RAD52KMT2A | |
| Bromide SCHEMBL22397860 | 1.00 | DNM1 (0.94) | DNM1HTTHSP90AA1RAD52KMT2A | |
| Bromide SCHEMBL22397869 | 1.00 | DNM1 (0.94) | DNM1HTTHSP90AA1RAD52KMT2A | |
| Bromide SCHEMBL21986903 | 1.00 | DNM1 (0.94) | DNM1HTTHSP90AA1RAD52KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 23973 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4746853-A1 | A LIPID DRUG DELIVERY SYSTEM FOR INCREASED ENDOSOMAL ESCAPE | MAX-PLANCK-GESELLSCHAFT ZUR FÖRDERUNG DER WISSENSCHAFTEN E.V. (DE) | 2026-05-27 | — | — | EP | claimed |
| EP-4746913-A1 | LIPID NANOPARTICLES COMPRISING POLYMER-CONJUGATED LIPIDS AND USES THEREOF | Pfizer Inc. (US) | 2026-05-27 | — | — | EP | claimed |
| US-20260139254-A1 | INTERFERING RNA FOR INHIBITING TOP1 GENE EXPRESSION AND USE THEREOF | JENKEM TECH CO LTD BEIJING (CN) | 2026-05-21 | — | — | US | claimed |
| CN-117427500-B | Amphiphilic molecule modified graphene-based ion selective membrane and preparation method and application thereof | 济南大学 | 2026-05-19 | — | — | CN | claimed |
| CN-122057013-A | Application of mycobacterium tuberculosis antigen Rv1471 in preparation of medicines or vaccines for preventing and/or treating diseases caused by mycobacterium infection | 上海市重大传染病和生物安全研究院 | 2026-05-19 | — | — | CN | claimed |
| CN-122055374-A | Lipid compounds and compositions for tissue-specific delivery of active substances | 韩国生命工学研究院 | 2026-05-15 | — | — | CN | claimed |
| CN-121732179-B | Preparation method of composite catalyst for synthesizing 2-methyltetrahydrofuran through furfural hydrogenation | 淄博齐塑环保科技有限公司 | 2026-05-12 | — | — | CN | claimed |
| EP-4734964-A1 | LIPID PARTICLES FOR DELIVERING A PAYLOAD | Repertoire Immune Medicines, Inc. (US) | 2026-05-06 | — | — | EP | claimed |
| US-12618001-B2 | Ultra-lightweight proppants | SAUDI ARABIAN OIL COMPANY (SA) | 2026-05-05 | — | — | US | claimed |
| WO-2026088119-A1 | LIPIDATED TLR7/8 MODULATORS AS ADJUVANTS AND USES THEREOF | PFIZER INC. (US) | 2026-04-30 | — | — | WO | claimed |
| EP-0299601-A1 | Method of determining a bacterial concentration and removing non-bacterial cells, and apparatus and reagents for the method | A/S Foss Electric Holding (DK) | 1989-01-18 | — | — | EP | claimed |
| US-4783220-A | Vesicle ink compositions | XEROX CORPORATION (US) | 1988-11-08 | — | — | US | claimed |
| EP-0273512-A2 | Stabilised adjuvant suspension comprising dimethyl dioctadecyl ammonium bromide | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1988-07-06 | — | — | EP | claimed |
| EP-0272896-A2 | Vesicle ink compositions | VESTAR, INC. (US) | 1988-06-29 | — | — | EP | claimed |
| EP-0097407-B1 | VACCINES AGAINST DISEASES CAUSING BACTERIA WITH CAPSULAR POLYSACCHARIDES AND PROCESS OF PREPARING THEM | Rijksuniversiteit Utrecht (NL) | 1987-05-13 | — | — | EP | claimed |
| US-4661270-A | Concentrated fabric softening composition and methods for making same | COLGATE-PALMOLIVE COMPANY (US) | 1987-04-28 | — | — | US | claimed |
| EP-0191536-A1 | Synthetic immunogen | AKZO N.V. (NL) | 1986-08-20 | — | — | EP | claimed |
| WO-1984000109-A1 | VACCINES AGAINST PATHOGENIC BACTERIA WITH CAPSULAR POLYSACCHARIDES AND PROCESS FOR THE PREPARATION THEREOF | UNIV UTRECHT (NL) | 1984-01-19 | — | — | WO | claimed |
| EP-0097407-A1 | Vaccines against diseases causing bacteria with capsular polysaccharides and process of preparing them | Rijksuniversiteit Utrecht (NL) | 1984-01-04 | — | — | EP | claimed |
| US-4203852-A | INORGANIC PEROXIDE BLEACH, CATIONIC SURFACTANT; FOR USE IN WASH CYCLE | COLGATE-PALMOLIVE COMPANY (US) | 1980-05-20 | — | — | US | claimed |