Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 2/20 | 0.34 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.30 |
| ▸ | ITK | Q08881 | 1/20 | 0.30 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16616856 | 0.87 | NTRK1 (0.33) | NTRK1NTRK3MAPK1MAP2K1ERBB2 | |
| SCHEMBL478887 | 0.76 | PDPK1 (0.54) | MAP2K1KDM4EPDPK1CYP3A4GAA | |
| SCHEMBL1290531 | 0.75 | KDM4E (0.52) | MAP2K1KDM4EPDPK1CYP3A4GAA | |
| SCHEMBL29733448 | 0.75 | KDM4E (0.52) | MAP2K1KDM4EPDPK1CYP3A4GAA | |
| SCHEMBL5662185 | 0.73 | PDPK1 (0.36) | NTRK3KDM4EPDPK1CYP3A4GAA | |
| SCHEMBL2305274 | 0.73 | KDM4E (0.32) | KDM4EPDPK1CYP3A4GAA | |
| SCHEMBL1694765 | 0.73 | CYP1A2 (0.43) | MAPK1KDM4EPDPK1CYP3A4GAA | |
| SCHEMBL1195920 | 0.73 | PDPK1 (0.32) | MAPK1KDM4EPDPK1CYP3A4GAA | |
| SCHEMBL18188335 | 0.73 | KDM4E (0.32) | KDM4EPDPK1CYP3A4GAA | |
| SCHEMBL694632 | 0.71 | LRRK2 (0.39) | LRRK2ITK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230026651-A1 | AMINO-PYRIMIDINE SKELETAL MUSCLE MODULATORS | CYTOKINETICS, INC. | 2023-01-26 | — | — | US | disclosed |
| US-11369565-B2 | Amino-pyrimidine skeletal muscle modulators | CYTOKINETICS, INC. (US) | 2022-06-28 | — | — | US | disclosed |
| US-20210045997-A1 | AMINO-PYRIMIDINE SKELETAL MUSCLE MODULATORS | CYTOKINETICS, INC. | 2021-02-18 | — | — | US | disclosed |
| US-10765624-B2 | Amino-pyrimidine skeletal muscle modulators | CYTOKINETICS, INC. (US) | 2020-09-08 | — | — | US | disclosed |
| EP-3698795-A1 | CERTAIN AMINO-PYRIMIDINES, COMPOSITIONS THEREOF, AND METHODS FOR THEIR USE | Cytokinetics, Inc. (US) | 2020-08-26 | — | — | EP | disclosed |
| EP-3127540-B1 | CERTAIN AMINO-PYRIMIDINES, COMPOSITIONS THEREOF, AND METHODS FOR THEIR USE | CYTOKINETICS INC (US) | 2020-01-29 | — | — | EP | disclosed |
| US-20190307677-A1 | AMINO-PYRIMIDINE SKELETAL MUSCLE MODULATORS | CYTOKINETICS INC (US) | 2019-10-10 | — | — | US | disclosed |
| EP-3127541-B1 | CERTAIN AMINO-PYRIDAZINES, COMPOSITIONS THEREOF, AND METHODS OF THEIR USE | CYTOKINETICS INC (US) | 2019-07-17 | — | — | EP | disclosed |
| US-20190167676-A1 | METHODS FOR IMPROVING RESISTANCE TO SKELETAL MUSCLE FATIGUE | CYTOKINETICS, INC. | 2019-06-06 | — | — | US | disclosed |
| US-10272030-B2 | Amino-pyrimidine skeletal muscle modulators | CYTOKINETICS, INC. (US) | 2019-04-30 | — | — | US | disclosed |
| US-5667936-A | FLUOROMETHYLATED HYDRAZIDE, HIGH CONTRAST, PROCESSING STABILITY, PRESERVABILITY | FUJI PHOTO FILM CO., LTD. (JP) | 1997-09-16 | — | — | US | disclosed |
| EP-0736798-A1 | Silver halide photographic material | FUJI PHOTO FILM CO., LTD. (JP) | 1996-10-09 | — | — | EP | disclosed |
| US-5338658-A | Nucleation agent | FUJI PHOTO FILM CO., LTD. (JP) | 1994-08-16 | — | — | US | disclosed |
| EP-0276842-B1 | SILVER HALIDE PHOTOGRAPHIC MATERIAL | FUJI PHOTO FILM CO., LTD. (JP) | 1992-07-29 | — | — | EP | disclosed |
| US-5035993-A | Quaternary ammonium salt nucleating agent | FUJI PHOTO FILM CO., LTD. (JP) | 1991-07-30 | — | — | US | disclosed |
| US-4987052-A | REDUCED AMOUNT OF BLACK PEPPERS | FUJI PHOTO FILM CO., LTD. (JP) | 1991-01-22 | — | — | US | disclosed |
| US-4877723-A | EMULSION LAYER CONTAINING AN ALKYNYL-SUBSTITUTED HETEROCYCLIC QUATERNARY AMMONIUM SALT; DIRECT POSITIVES; REVERSAL | FUJI PHOTO FILM CO., LTD. (JP) | 1989-10-31 | — | — | US | disclosed |
| US-4859579-A | Silver halide photographic material | FUJI PHOTO FILM CO., LTD. (JP) | 1989-08-22 | — | — | US | disclosed |
| US-4828973-A | DIRECT POSITIVES WITH REVERSAL PROPERTIES | FUJI PHOTO FILM CO., LTD. (JP) | 1989-05-09 | — | — | US | disclosed |
| EP-0276842-A2 | Silver halide photographic material | FUJI PHOTO FILM CO., LTD. (JP) | 1988-08-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11369565-B2 | Amino-pyrimidine skeletal muscle modulators | MUSK, PYGM, TNNC1 | NTRK1 4700/4885NTRK3 4516/4885MAPK1 1025/4885 |
| US-10765624-B2 | Amino-pyrimidine skeletal muscle modulators | MUSK, PYGM, TNNC1 | NTRK1 4604/4885NTRK3 4190/4885MAPK1 1225/4885 |
| US-20230026651-A1 | AMINO-PYRIMIDINE SKELETAL MUSCLE MODULATORS | MUSK, PYGM, TNNC1 | NTRK1 4604/4885NTRK3 4190/4885MAPK1 1225/4885 |
| US-10272030-B2 | Amino-pyrimidine skeletal muscle modulators | MUSK, PYGM, TNNC1 | NTRK1 4604/4885NTRK3 4190/4885MAPK1 1225/4885 |
| US-20190167676-A1 | METHODS FOR IMPROVING RESISTANCE TO SKELETAL MUSCLE FATIGUE | TNNC1, TNNI3, TNNT2 | NTRK1 3027/4885NTRK3 1431/4885MAPK1 2703/4885 |
| US-20190307677-A1 | AMINO-PYRIMIDINE SKELETAL MUSCLE MODULATORS | MUSK, PYGM, TNNC1 | NTRK1 4604/4885NTRK3 4190/4885MAPK1 1225/4885 |
| US-20210045997-A1 | AMINO-PYRIMIDINE SKELETAL MUSCLE MODULATORS | MUSK, PYGM, TNNC1 | NTRK1 4700/4885NTRK3 4516/4885MAPK1 1025/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.