SCHEMBL428119

SCHEMBL428119

CO[Si](CCCOCC(O)CO)(CCCOCC(O)CO)OC

nearest known ligand 0.55

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.55
HTT P42858 1/20 0.37
LMNA P02545 2/20 0.35
CYP1A2 P05177 2/20 0.35
AGTR1 P30556 1/20 0.35
PLA2G2C Q5R387 1/20 0.33
LPAR5 Q9H1C0 1/20 0.33
HSD17B10 Q99714 1/20 0.32
KDM4E B2RXH2 1/20 0.31
DUSP3 P51452 1/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
CYP3A4 P08684 1/20 0.30
CYP2C19 P33261 1/20 0.30
TSHR P16473 1/20 0.30
MAPK1 P28482 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31026687 0.91 USP2 (0.54) USP2HTTLMNACYP1A2AGTR1
SCHEMBL430465 0.85 USP2 (0.55) USP2HTTLMNACYP1A2AGTR1
SCHEMBL25638703 0.84 USP2 (0.53) USP2HTTLMNACYP1A2AGTR1
SCHEMBL14089863 0.84 USP2 (0.53) USP2HTTLMNACYP1A2AGTR1
SCHEMBL16588236 0.84 USP2 (0.53) USP2HTTLMNACYP1A2AGTR1
SCHEMBL1106391 0.82 USP2 (0.51) USP2HTTLMNACYP1A2AGTR1
SCHEMBL373637 0.81 USP2 (0.58) USP2HTTLMNACYP1A2AGTR1
SCHEMBL13044735 0.79 USP2 (0.56) USP2HTTLMNACYP1A2AGTR1
SCHEMBL14962633 0.79 USP2 (0.56) USP2HTTLMNACYP1A2AGTR1
SCHEMBL5854880 0.79 USP2 (0.55) USP2HTTLMNACYP1A2AGTR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10702467-B2 Emulsion containing organosilicon-based portions of hollow spheres L'ORÉAL (FR) 2020-07-07 US disclosed
EP-3021948-B1 OIL/OIL EMULSIONS CONTAINING PARTICLES WITH A BREAKAGE OF CURVATURE, COMPOSITIONS COMPRISING THEM AND USE OF THE PARTICLES FOR STABILIZING O/O EMULSIONS OREAL (FR) 2019-08-21 EP disclosed
US-20170304183-A1 EMULSION CONTAINING ORGANOSILICON-BASED PORTIONS OF HOLLOW SPHERES L'ORÉAL (FR) 2017-10-26 US disclosed
US-9622946-B2 Emulsion containing organosilicon-based portions of hollow spheres L'OREAL (FR) 2017-04-18 US disclosed
EP-2462197-B1 COMPOSITE PIGMENT AND METHOD FOR PREPARATION THEREOF ORÉAL L (FR) 2016-09-21 EP disclosed
WO-2016116475-A1 O/O EMULSION CONTAINING MICROPARTICLES WITH A BREAK IN THE CURVATURED PART, COMPOSITIONS COMPRISING SAME AND USE OF MICROPARTICLES FOR STABILIZING THE O/O EMULSIONS L'OREAL (FR) 2016-07-28 WO disclosed
WO-2016116488-A1 OIL/OIL EMULSION COMPRISING SOLID MICROPARTICLES, AT LEAST ONE HYDROCARBON-BASED RESIN, AT LEAST A FIRST OILY PHASE AND AT LEAST A SECOND OILY PHASE L'OREAL (FR) 2016-07-28 WO disclosed
WO-2016116492-A1 OIL/OIL EMULSION COMPRISING SOLID MICROPARTICLES, AT LEAST A FIRST OILY PHASE, AT LEAST A SECOND OILY PHASE AND AT LEAST A THIRD OILY PHASE THAT ARE MUTUALLY IMMISCIBLE L'OREAL (FR) 2016-07-28 WO disclosed
US-20160158118-A1 OIL/OIL EMULSIONS CONTAINING PARTICLES WITH A BREAKAGE OF CURVATURE, COMPOSITIONS COMPRISING THEM AND USE OF THE PARTICLES FOR STABILIZING O/O EMULSIONS L'OREAL (FR) 2016-06-09 US disclosed
EP-3021948-A1 OIL/OIL EMULSIONS CONTAINING PARTICLES WITH A BREAKAGE OF CURVATURE, COMPOSITIONS COMPRISING THEM AND USE OF THE PARTICLES FOR STABILIZING O/O EMULSIONS L'OREAL (FR) 2016-05-25 EP disclosed
US-20060293431-A1 Cosmetic composition comprising silicone particles L'OREAL S.A. (FR) 2006-12-28 US disclosed
EP-1731136-A1 Cosmetic composition containing hollow organosilicon particles L'OREAL (FR) 2006-12-13 EP disclosed
EP-1642620-A1 Hair cosmetic composition comprising hollow particles and silicone fixing polyurethane L'OREAL, S.A. (FR) 2006-04-05 EP disclosed
EP-1642619-A1 Hair cosmetic composition comprising hollow particles and non-silicone fixing polymer L'OREAL (FR) 2006-04-05 EP disclosed
US-20050220741-A1 Cosmetic composition comprising concave particles L'OREAL S.A. (FR) 2005-10-06 US disclosed
US-20050220740-A1 Cosmetic composition comprising concave particles L'OREAL S.A. (FR) 2005-10-06 US disclosed
EP-1579841-A1 Cosmetic composition comprising concave particles L'OREAL (FR) 2005-09-28 EP disclosed
EP-1579849-A1 Cosmetic compositions comprising concave particles. L'OREAL (FR) 2005-09-28 EP disclosed
US-20050118218-A1 Emulsion containing organosilicon-based portions of hollow spheres L'OREAL (FR) 2005-06-02 US disclosed
EP-1530961-A2 Emulsion containing hollow organosilicon particles L'OREAL (FR) 2005-05-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160158118-A1 OIL/OIL EMULSIONS CONTAINING PARTICLES WITH A BREAKAGE OF CURVATURE, COMPOSITIONS COMPRISING THEM AND USE OF THE PARTICLES FOR STABILIZING O/O EMULSIONS NONO, SQLE, PFN1 USP2 2241/4885HTT 2903/4885LMNA 808/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.