Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.48 |
| ▸ | NQO2 | P16083 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.46 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | FDPS | P14324 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2564338 | 1.00 | ALDH1A1 (0.56) | ALDH1A1TSHRGAATDP1CYP1A2 | |
| SCHEMBL2564332 | 1.00 | ALDH1A1 (0.56) | ALDH1A1TSHRGAATDP1CYP1A2 | |
| SCHEMBL221732 | 0.89 | PDE4B (0.46) | ALDH1A1TSHRGAATDP1CYP1A2 | |
| SCHEMBL222376 | 0.89 | PDE4B (0.46) | ALDH1A1TSHRGAATDP1CYP1A2 | |
| SCHEMBL220599 | 0.89 | TDP1 (0.44) | ALDH1A1TSHRGAATDP1CYP1A2 | |
| SCHEMBL221130 | 0.89 | TDP1 (0.44) | ALDH1A1TSHRGAATDP1CYP1A2 | |
| SCHEMBL221731 | 0.89 | PDE4B (0.46) | ALDH1A1TSHRGAATDP1CYP1A2 | |
| SCHEMBL218831 | 0.88 | ALDH1A1 (0.61) | ALDH1A1TDP1CYP1A2NQO2SMN1; SMN2 | |
| SCHEMBL220185 | 0.88 | ALDH1A1 (0.61) | ALDH1A1TDP1CYP1A2NQO2SMN1; SMN2 | |
| SCHEMBL221031 | 0.85 | TDP1 (0.42) | ALDH1A1TSHRGAATDP1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260043010-A1 | ENONE REDUCTASES | CODEXIS, INC. (US) | 2026-02-12 | — | — | US | disclosed |
| US-12371674-B2 | Enone reductases | CODEXIS, INC. (US) | 2025-07-29 | — | — | US | disclosed |
| US-20210324344-A1 | ENONE REDUCTASES | INNOVATUS LIFE SCIENCES LENDING FUND I, LP, AS COLLATERAL AGENT | 2021-10-21 | — | — | US | disclosed |
| US-10995321-B2 | Enone reductases | CODEXIS, INC. (US) | 2021-05-04 | — | — | US | disclosed |
| US-20200040311-A1 | ENONE REDUCTASES | INNOVATUS LIFE SCIENCES LENDING FUND I, LP, AS COLLATERAL AGENT | 2020-02-06 | — | — | US | disclosed |
| US-20180312815-A1 | ENONE REDUCTASES | INNOVATUS LIFE SCIENCES LENDING FUND I, LP, AS COLLATERAL AGENT | 2018-11-01 | — | — | US | disclosed |
| US-10035988-B2 | Enone reductases | CODEXIS, INC. (US) | 2018-07-31 | — | — | US | disclosed |
| US-20170175087-A1 | ENONE REDUCTASES | INNOVATUS LIFE SCIENCES LENDING FUND I, LP, AS COLLATERAL AGENT | 2017-06-22 | — | — | US | disclosed |
| US-9617568-B2 | Enone reductases | CODEXIS, INC. (US) | 2017-04-11 | — | — | US | disclosed |
| US-20160273007-A1 | ENONE REDUCTASES | INNOVATUS LIFE SCIENCES LENDING FUND I, LP, AS COLLATERAL AGENT | 2016-09-22 | — | — | US | disclosed |
| US-20150315613-A1 | ENONE REDUCTASES | INNOVATUS LIFE SCIENCES LENDING FUND I, LP, AS COLLATERAL AGENT | 2015-11-05 | — | — | US | disclosed |
| US-9121045-B2 | Enone reductases | CODEXIS, INC. (US) | 2015-09-01 | — | — | US | disclosed |
| EP-2382308-B1 | ENONE REDUCTASES | CODEXIS INC (US) | 2015-03-04 | — | — | EP | disclosed |
| US-20150031095-A1 | ENONE REDUCTASES | INNOVATUS LIFE SCIENCES LENDING FUND I, LP, AS COLLATERAL AGENT | 2015-01-29 | — | — | US | disclosed |
| US-8883475-B2 | Enone reductases | CODEXIS, INC. (US) | 2014-11-11 | — | — | US | disclosed |
| US-20130115663-A1 | ENONE REDUCTASES | CODEXIS, INC. (US) | 2013-05-09 | — | — | US | disclosed |
| US-8329438-B2 | Enone reductases | CODEXIS, INC. (US) | 2012-12-11 | — | — | US | disclosed |
| EP-2382308-A2 | ENONE REDUCTASES | Codexis, Inc. (US) | 2011-11-02 | — | — | EP | disclosed |
| US-20100190218-A1 | ENONE REDUCTASES | CODEXIS, INC. (US) | 2010-07-29 | — | — | US | disclosed |
| WO-2010075574-A2 | ENONE REDUCTASES | CODEXIS, INC. (US) | 2010-07-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180312815-A1 | ENONE REDUCTASES | ENO1, DCXR, RRM2B | ALDH1A1 1267/4885TSHR 2078/4885GAA 1349/4885 |
| US-10995321-B2 | Enone reductases | ENO1, DCXR, RRM2B | ALDH1A1 1267/4885TSHR 2078/4885GAA 1349/4885 |
| US-20200040311-A1 | ENONE REDUCTASES | ENO1, DCXR, RRM2B | ALDH1A1 1267/4885TSHR 2078/4885GAA 1349/4885 |
| US-12371674-B2 | Enone reductases | ENO1, DCXR, RRM2B | ALDH1A1 1267/4885TSHR 2078/4885GAA 1349/4885 |
| US-20260043010-A1 | ENONE REDUCTASES | DCXR, ENY2, UPF1 | ALDH1A1 2992/4885TSHR 1217/4885GAA 3308/4885 |
| US-20210324344-A1 | ENONE REDUCTASES | ENO1, DCXR, RRM2B | ALDH1A1 1267/4885TSHR 2078/4885GAA 1349/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.