Dermatan Sulfate

Dermatan Sulfate

SCHEMBL25645152

COC1OC(CO)C(OS(=O)(=O)O)[C@H](O[C@@H]2OC(C(=O)O)[C@@H](OC)[C@@H](O)C2O)[C@@H]1NC(C)=O

nearest known ligand 0.54

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MDK P21741 4/20 0.54
BDNF P23560 3/20 0.54
PTN P21246 2/20 0.54
F10 P00742 2/20 0.51
LGALS3 P17931 7/20 0.45
LGALS7; LGALS7B P47929 2/20 0.43
LGALS1 P09382 1/20 0.43
SERPINC1 P01008 1/20 0.43
LGALS9 O00182 2/20 0.42
LGALS8 O00214 1/20 0.42
LGALS4 P56470 1/20 0.42
CXCL10 P02778 1/20 0.39
CXCL8 P10145 1/20 0.39
CCL2 P13500 1/20 0.39
CCL5 P13501 1/20 0.39
CXCL12 P48061 1/20 0.39
CD69 Q07108 1/20 0.38
AMY2A P04746 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dermatan Sulfate SCHEMBL10157447 1.00 MDK (0.54) MDKBDNFPTNF10LGALS3
Dermatan Sulfate SCHEMBL15144387 1.00 MDK (0.54) MDKBDNFPTNF10LGALS3
SCHEMBL27097993 0.93 BDNF (0.49) MDKBDNFPTNF10LGALS3
Dermatan SCHEMBL16311126 0.89 LGALS3 (0.49) MDKBDNFPTNF10LGALS3
Dermatan SCHEMBL29360360 0.89 LGALS3 (0.49) MDKBDNFPTNF10LGALS3
Dermatan SCHEMBL13472480 0.89 LGALS3 (0.49) MDKBDNFPTNF10LGALS3
Dermatan SCHEMBL19184706 0.89 LGALS3 (0.49) MDKBDNFPTNF10LGALS3
Dermatan SCHEMBL12691925 0.89 LGALS3 (0.49) MDKBDNFPTNF10LGALS3
Dermatan SCHEMBL19846466 0.89 LGALS3 (0.49) MDKBDNFPTNF10LGALS3
Dermatan SCHEMBL18232151 0.89 LGALS3 (0.49) MDKBDNFPTNF10LGALS3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11672833-B2 Edible bird's nest extract and method of extraction LIM KAH MENG (SG) 2023-06-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11672833-B2 Edible bird's nest extract and method of extraction BROX, BECN1, EPHA5 MDK 2943/4885BDNF 1888/4885PTN 1708/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.