Dermatan

Dermatan

SCHEMBL12691925

CO[C@@H]1OC(CO)[C@@H](O)[C@H](O[C@@H]2OC(C(=O)O)[C@@H](OC)[C@H](O)C2O)C1NC(C)=O

nearest known ligand 0.49

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
LGALS3 P17931 7/20 0.49
LGALS7; LGALS7B P47929 2/20 0.48
LGALS1 P09382 1/20 0.48
BDNF P23560 3/20 0.47
MDK P21741 3/20 0.47
PTN P21246 2/20 0.47
LGALS8 O00214 3/20 0.47
LGALS4 P56470 1/20 0.47
LGALS9 O00182 2/20 0.47
MAPK1 P28482 2/20 0.45
CD69 Q07108 1/20 0.44
F10 P00742 1/20 0.44
ALDH1A1 P00352 1/20 0.43
THRB P10828 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dermatan SCHEMBL16311126 1.00 LGALS3 (0.49) LGALS3LGALS7; LGALS7BLGALS1BDNFMDK
Dermatan SCHEMBL29360360 1.00 LGALS3 (0.49) LGALS3LGALS7; LGALS7BLGALS1BDNFMDK
Dermatan SCHEMBL13472480 1.00 LGALS3 (0.49) LGALS3LGALS7; LGALS7BLGALS1BDNFMDK
Dermatan SCHEMBL18232151 1.00 LGALS3 (0.49) LGALS3LGALS7; LGALS7BLGALS1BDNFMDK
Dermatan SCHEMBL19846466 1.00 LGALS3 (0.49) LGALS3LGALS7; LGALS7BLGALS1BDNFMDK
Dermatan SCHEMBL19184706 1.00 LGALS3 (0.49) LGALS3LGALS7; LGALS7BLGALS1BDNFMDK
SCHEMBL24844372 0.98 BDNF (0.50) LGALS3LGALS7; LGALS7BLGALS1BDNFMDK
SCHEMBL14497205 0.98 BDNF (0.50) LGALS3LGALS7; LGALS7BLGALS1BDNFMDK
SCHEMBL25785578 0.98 BDNF (0.50) LGALS3LGALS7; LGALS7BLGALS1BDNFMDK
SCHEMBL19295777 0.96 BDNF (0.49) LGALS3LGALS7; LGALS7BLGALS1BDNFMDK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240026404-A1 CELLULAR GLYCOSAMINOGLYCAN COMPOSITIONS AND METHODS OF MAKING AND USING TEGA THERAPEUTICS, INC. 2024-01-25 US disclosed
US-11707473-B2 Method for the manufacture and use of a bionic hydrogel composition for medical applications Qventis GmbH (DE) 2023-07-25 US disclosed
US-20180168316-A1 Packaged Skin Treatment Composition And Method ELC MANAGEMENT LLC 2018-06-21 US disclosed
US-9492586-B2 Derivatives of hyaluronic acid capable of forming hydrogels CONTIPRO BIOTECH S.R.O. (CZ) 2016-11-15 US disclosed
US-9433644-B2 Formulations and methods for treating oral inflammation, injury, or pain RUTGILLI PHARMACEUTICALS, LLC (US) 2016-09-06 US disclosed
US-20150119783-A1 Method of Preparation of Polysaccharide Fibres, Wound Covers that Contain Them, Method of Manufacturing of Wound Covers, and Apparatus for Preparation of Polysaccharide Fibres CONTIPRO BIOTECH S.R.O. (CZ) 2015-04-30 US disclosed
US-20150030694-A1 FORMULATIONS AND METHODS FOR TREATING ORAL INFLAMMATION, INJURY, OR PAIN INVADO LABORATORIES, LLC 2015-01-29 US disclosed
US-20150000561-A1 Derivates Based on Hyaluronic Acid, Capable of Forming Hydrogels, Method of Preparation Thereof, Hydrogels Based on Said Derivatives, Method of Preparation Thereof and Use CONTIPRO A.S. (CZ) 2015-01-01 US disclosed
US-20140363502-A1 Resveratrol-Containing Compositions and Methods of Use for Treatment of Macular Degeneration RESVERATROL PARTNERS LLC (US) 2014-12-11 US disclosed
US-20120245518-A1 PHARMACEUTICAL COMPOSITION FOR THE TREATMENT OF BLADDER DISORDERS RITCHER GEDEON NYRT. (HU) 2012-09-27 US disclosed
US-20100248260-A1 GLYCOSAMINOGLYCAN-COATED PARTICLES AND USES THEREOF MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2010-09-30 US disclosed
US-20100173228-A1 Nanotube and Carbon Layer Nanostructured Composites UNIVERSITY OF WOLLONGONG (AU) 2010-07-08 US disclosed
US-20100087798-A1 SYSTEMS, METHODS AND DEVICES FOR USING A FLOWABLE MEDIUM FOR DISTENDING A HOLLOW ORGAN INTERLACE MEDICAL, INC. (US) 2010-04-08 US disclosed
US-20100068461-A1 NANOSTRUCTURED COMPOSITES UNIVERSITY OF WOLLONGONG (AU) 2010-03-18 US disclosed
US-20100022471-A1 Oral Moisturizer for Alleviating Dry Mouth SAGE PRODUCTS INC. (US) 2010-01-28 US disclosed
US-20100023101-A1 BIOCOMPATIBLE COMPOSITES UNIVERSITY OF WOLLONGONG (AU) 2010-01-28 US disclosed
US-20090169585-A1 Resveratrol-Containing Compositions And Their Use In Modulating Gene Product Concentration Or Activity RESVERATROL PARTNERS, LLC (US) 2009-07-02 US disclosed
US-20070203094-A1 Esters Of Hyaluronic Acid With Rhein, Process For Their Preparation And Compositions Comprising The Same LABROATOIRE MEDIDOM S.A. (CH) 2007-08-30 US disclosed
US-7238677-B2 Prevention of urogenital infections KIMBERLY-CLARK WORLDWIDE, INC. (US) 2007-07-03 US disclosed
US-20070123488-A1 Pharmaceutical composition comprising a zinc-hyaluronate complex for the treatment of multiple sclerosis RICHTER GEDEON VEGYESZETI GYAR RT. (HU) 2007-05-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100023101-A1 BIOCOMPATIBLE COMPOSITES F12, MATR3, FIBP LGALS3 1222/4885LGALS7; LGALS7B 1728/4885LGALS1 1025/4885
US-20070123488-A1 Pharmaceutical composition comprising a zinc-hyaluronate complex for the treatment of multiple sclerosis CD44, SLC30A7, SLC30A6 LGALS3 753/4885LGALS7; LGALS7B 881/4885LGALS1 987/4885
US-20090169585-A1 Resveratrol-Containing Compositions And Their Use In Modulating Gene Product Concentration Or Activity IGFBP6, SIRT6, IP6K1 LGALS3 1913/4885LGALS7; LGALS7B 2381/4885LGALS1 1295/4885
US-20150030694-A1 FORMULATIONS AND METHODS FOR TREATING ORAL INFLAMMATION, INJURY, OR PAIN CD44, TRPV1, IL6 LGALS3 344/4885LGALS7; LGALS7B 1104/4885LGALS1 528/4885
US-20120245518-A1 PHARMACEUTICAL COMPOSITION FOR THE TREATMENT OF BLADDER DISORDERS SLC30A7, SLC39A11, SLC30A6 LGALS3 316/4885LGALS7; LGALS7B 353/4885LGALS1 424/4885
US-20140363502-A1 Resveratrol-Containing Compositions and Methods of Use for Treatment of Macular Degeneration IGFBP6, SIRT6, STRA6 LGALS3 1262/4885LGALS7; LGALS7B 2480/4885LGALS1 1032/4885
US-20070203094-A1 Esters Of Hyaluronic Acid With Rhein, Process For Their Preparation And Compositions Comprising The Same CD44, RDX, RALA LGALS3 2434/4885LGALS7; LGALS7B 1901/4885LGALS1 2238/4885
US-20240026404-A1 CELLULAR GLYCOSAMINOGLYCAN COMPOSITIONS AND METHODS OF MAKING AND USING CD44, CSGALNACT1, HPSE LGALS3 64/4885LGALS7; LGALS7B 169/4885LGALS1 143/4885
US-20100022471-A1 Oral Moisturizer for Alleviating Dry Mouth TAS2R40, TAS2R60, TREH LGALS3 2089/4885LGALS7; LGALS7B 2456/4885LGALS1 1667/4885
US-11707473-B2 Method for the manufacture and use of a bionic hydrogel composition for medical applications HLCS, CD44, PLOD3 LGALS3 168/4885LGALS7; LGALS7B 145/4885LGALS1 63/4885
US-20180168316-A1 Packaged Skin Treatment Composition And Method CUTA, KRT18, EXOSC5 LGALS3 3777/4885LGALS7; LGALS7B 3325/4885LGALS1 4001/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.