Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.58 |
| ▸ | TSHR | P16473 | 4/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | G6PC1 | P35575 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12414402 | 0.80 | ALDH1A1 (0.64) | ALDH1A1TSHRMAPK1CYP3A4TDP1 | |
| SCHEMBL384906 | 0.80 | ALDH1A1 (0.64) | ALDH1A1TSHRMAPK1CYP3A4TDP1 | |
| SCHEMBL19033246 | 0.77 | ALDH1A1 (0.54) | ALDH1A1TSHRMAPK1CYP3A4TDP1 | |
| SCHEMBL28075013 | 0.76 | PYCR1 (0.52) | ALDH1A1TSHRRAB9AHRH3KDM4E | |
| SCHEMBL21078333 | 0.76 | ALDH1A1 (0.58) | ALDH1A1TSHRMAPK1CYP3A4TDP1 | |
| SCHEMBL25588075 | 0.76 | PYCR1 (0.52) | ALDH1A1TDP1HRH3 | |
| SCHEMBL11086907 | 0.75 | ALDH1A1 (0.64) | ALDH1A1TSHRMAPK1CYP3A4TDP1 | |
| SCHEMBL28074416 | 0.75 | TSHR (0.64) | ALDH1A1TSHRCYP3A4RAB9AKDM4E | |
| SCHEMBL21078332 | 0.74 | ALDH1A1 (0.56) | ALDH1A1TSHRMAPK1CYP3A4TDP1 | |
| SCHEMBL17886950 | 0.74 | ALDH1A1 (0.56) | ALDH1A1TSHRMAPK1CYP3A4TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11679158-B2 | Biodegradable lipids for the delivery of active agents | ALNYLAM PHARMACEUTICALS, INC. (US) | 2023-06-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11679158-B2 | Biodegradable lipids for the delivery of active agents | LIPA, APOB, CETP | ALDH1A1 3151/4885TSHR 2733/4885MAPK1 4707/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.