Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 13/20 | 0.52 |
| ▸ | JAK3 | P52333 | 2/20 | 0.37 |
| ▸ | GPR4 | P46093 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 4/20 | 0.35 |
| ▸ | CTSS | P25774 | 5/20 | 0.35 |
| ▸ | CTSB | P07858 | 2/20 | 0.35 |
| ▸ | KMO | O15229 | 1/20 | 0.34 |
| ▸ | LCK | P06239 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29324978 | 0.85 | JAK3 (0.53) | CTSKJAK3GPR4LCK | |
| SCHEMBL6241634 | 0.73 | CTSK (0.40) | CTSKCTSLCTSS | |
| SCHEMBL5794080 | 0.71 | CTSK (0.51) | CTSKGPR4CTSLCTSSCTSB | |
| SCHEMBL2228524 | 0.71 | CTSK (0.50) | CTSKGPR4KMO | |
| SCHEMBL27227021 | 0.71 | JAK3 (0.40) | CTSKJAK3LCK | |
| SCHEMBL154166 | 0.70 | CTSL (0.38) | CTSKCTSLCTSS | |
| SCHEMBL31627588 | 0.69 | CTSK (0.38) | CTSKJAK3CTSLCTSSCTSB | |
| SCHEMBL31061062 | 0.69 | CTSK (1.00) | CTSKCTSLCTSSCTSB | |
| SCHEMBL2566470 | 0.67 | CTSK (0.47) | CTSKGPR4CTSSKMO | |
| SCHEMBL1509580 | 0.66 | CTSK (0.49) | CTSKCTSSKMO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2382240-A2 | POLYMERS FUNCTIONALIZED WITH NITRILE COMPOUNDS CONTAINING A PROTECTED AMINO GROUP | Bridgestone Corporation (JP) | 2011-11-02 | — | — | EP | disclosed |
| WO-2010085622-A9 | POLYMERS FUNCTIONALIZED WITH NITRILE COMPOUNDS CONTAINING A PROTECTED AMINO GROUP | BRIDGESTONE CORPORATION (JP) | 2010-12-23 | — | — | WO | disclosed |
| WO-2010085622-A2 | POLYMERS FUNCTIONALIZED WITH NITRILE COMPOUNDS CONTAINING A PROTECTED AMINO GROUP | BRIDGESTONE CORPORATION (JP) | 2010-07-29 | — | — | WO | disclosed |