Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | TACR1 | P25103 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.37 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.37 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HTR1D | P28221 | 2/20 | 0.36 |
| ▸ | ACP3 | P15309 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13075267 | 0.80 | ACHE (0.41) | ALDH1A1CYP2D6AOC3ACHESLC6A2 | |
| SCHEMBL8285888 | 0.80 | ALDH1A1 (0.47) | ALDH1A1CYP2D6TACR1TAS1R3TAS1R1 | |
| SCHEMBL4578363 | 0.80 | ALDH1A1 (0.47) | ALDH1A1CYP2D6TACR1TAS1R3TAS1R1 | |
| SCHEMBL8285875 | 0.80 | ALDH1A1 (0.47) | ALDH1A1CYP2D6TACR1TAS1R3TAS1R1 | |
| SCHEMBL24453717 | 0.79 | USP1 (0.43) | ALDH1A1CYP2D6AOC3ACHESLC6A2 | |
| SCHEMBL14262065 | 0.79 | USP1 (0.43) | ALDH1A1CYP2D6AOC3ACHESLC6A2 | |
| SCHEMBL11628438 | 0.79 | AOC3 (0.41) | CYP2D6AOC3ACHESLC6A2SLC6A4 | |
| SCHEMBL18593504 | 0.78 | PNMT (0.45) | SLC6A2SLC6A4 | |
| SCHEMBL20931331 | 0.77 | ALDH1A1 (0.49) | ALDH1A1CYP2D6AOC3ACHEADRB2 | |
| SCHEMBL13002295 | 0.77 | ALDH1A1 (0.49) | ALDH1A1CYP2D6AOC3ACHEADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023107557-A1 | COMPOUNDS AND COMPOSITIONS THAT INHIBIT PIKFYVE | Kineta, Inc. (US) | 2023-06-15 | — | — | WO | disclosed |