Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | LDHA | P00338 | 1/20 | 0.37 |
| ▸ | LDHB | P07195 | 1/20 | 0.37 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.36 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.36 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2516349 | 0.82 | KMT2A (0.42) | KMT2ACYP26A1HPGD | |
| SCHEMBL25647654 | 0.74 | FDPS (0.40) | KMT2AMEN1LDHALDHBSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL25222775 | 0.73 | FDPS (0.39) | KMT2AMEN1LDHALDHBSMN1; SMN2 | |
| SCHEMBL25227617 | 0.70 | KLK5 (0.43) | ITGA4ITGB7 | |
| SCHEMBL31146320 | 0.68 | PSMB5 (0.47) | HDAC1HDAC2HDAC6HDAC3HDAC8 | |
| SCHEMBL25225956 | 0.68 | PSMB5 (0.47) | HDAC1HDAC2HDAC6HDAC3HDAC8 | |
| SCHEMBL27980070 | 0.67 | FDPS (0.41) | KMT2AMEN1TP53LDHALDHB | |
| SCHEMBL18117397 | 0.67 | FDPS (0.38) | KMT2AMEN1LDHALDHBSMN1; SMN2 | |
| SCHEMBL14853086 | 0.67 | FDPS (0.38) | KMT2AMEN1LDHALDHBSMN1; SMN2 | |
| SCHEMBL690630 | 0.67 | ITGA4 (0.43) | KMT2AMEN1LDHALDHBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2001875-A2 | GLUCOKINASE ACTIVATORS | Takeda San Diego, Inc. (US) | 2008-12-17 | — | — | EP | disclosed |
| WO-2007104034-A2 | GLUCOKINASE ACTIVATORS | TAKEDA SAN DIEGO, INC. (US) | 2007-09-13 | — | — | WO | disclosed |