Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH5 | P11766 | 8/20 | 0.43 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.40 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.40 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.40 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 2/20 | 0.38 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25650489 | 0.79 | OGA (0.44) | TBXAS1CYP3A4BAZ2BHTTMEN1 | |
| SCHEMBL25650245 | 0.75 | STING1 (0.64) | CYP3A4STING1 | |
| SCHEMBL25650246 | 0.72 | STING1 (0.57) | STING1 | |
| SCHEMBL8150666 | 0.72 | LMNA (0.44) | ENPP2MKNK1MKNK2CYP3A4IDO1 | |
| SCHEMBL18114204 | 0.70 | PIK3CD (0.48) | ADH5TBXAS1CYP3A4BAZ2BHTT | |
| SCHEMBL31216537 | 0.69 | CHEK1 (0.48) | ADH5 | |
| SCHEMBL31216541 | 0.69 | ADH5 (0.42) | ADH5ENPP2MKNK1MKNK2TBXAS1 | |
| SCHEMBL7020662 | 0.66 | DAO (0.35) | TSHR | |
| SCHEMBL28766887 | 0.65 | ADH5 (0.47) | ADH5ENPP2MKNK1MKNK2CYP3A4 | |
| SCHEMBL2628931 | 0.65 | CYP3A4 (0.39) | ENPP2MKNK1MKNK2CYP3A4IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023103850-A1 | SMALL MOLECULE STING AGONIST, PREPARATION METHOD THEREFOR, AND APPLICATION | 中国科学院上海药物研究所 | 2023-06-15 | — | — | WO | disclosed |