Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OGA | O60502 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | MITF | O75030 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | CDC7 | O00311 | 4/20 | 0.37 |
| ▸ | DBF4 | Q9UBU7 | 4/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25650490 | 0.79 | ADH5 (0.43) | MEN1KMT2ATBXAS1HTTCYP3A4 | |
| SCHEMBL5868906 | 0.76 | RAB9A (0.51) | OGAKDM4EMEN1MITFALDH1A1 | |
| SCHEMBL5800533 | 0.71 | HTT (0.71) | KDM4EMEN1MITFALDH1A1MAPT | |
| SCHEMBL29824206 | 0.71 | MAPT (0.46) | KDM4EMEN1MITFALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL28276875 | 0.70 | HTT (0.69) | KDM4EMEN1MITFALDH1A1MAPT | |
| SCHEMBL4315953 | 0.70 | ALDH1A1 (0.46) | KDM4EMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL299130 | 0.70 | ALDH1A1 (0.46) | KDM4EALDH1A1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL25417081 | 0.70 | OGA (0.52) | OGAKDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL1818667 | 0.69 | TBXAS1 (0.48) | KDM4EALDH1A1TBXAS1CDC7DBF4 | |
| SCHEMBL25650163 | 0.69 | STING1 (0.51) | KDM4EMAPTSMN1; SMN2L3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023103850-A1 | SMALL MOLECULE STING AGONIST, PREPARATION METHOD THEREFOR, AND APPLICATION | 中国科学院上海药物研究所 | 2023-06-15 | — | — | WO | disclosed |