Biphenyl

Biphenyl

SCHEMBL2565443

CC(C)(C)Oc1ccc(Cl)cc1.S.c1ccc(-c2ccccc2)cc1

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 3/20 0.52
PPARA Q07869 10/20 0.50
CYP3A4 P08684 2/20 0.50
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
CYP2D6 P10635 1/20 0.50
MAPT P10636 1/20 0.50
CYP2C19 P33261 1/20 0.50
PPARG P37231 3/20 0.47
FABP2 P12104 1/20 0.44
SLC22A12 Q96S37 1/20 0.44
ADAMTS5 Q9UNA0 1/20 0.43
ADORA3 P0DMS8 1/20 0.42
ADORA2A P29274 1/20 0.42
ABCB11 O95342 1/20 0.40
TSHR P16473 1/20 0.40
HTR2A P28223 1/20 0.40
PMP22 Q01453 1/20 0.40
GLA P06280 1/20 0.40
ALDH1A1 P00352 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7861289 0.86 NPC1 (0.43) CYP1A2PPARACYP3A4MEN1KMT2A
SCHEMBL196705 0.85 PPARA (0.57) CYP1A2PPARACYP3A4MEN1KMT2A
SCHEMBL4820655 0.83 PPARA (0.55) CYP1A2PPARACYP3A4MEN1KMT2A
SCHEMBL13945697 0.79 MAOA (0.52) CYP1A2PPARACYP3A4MEN1KMT2A
Hydrogen Sulfide SCHEMBL27589515 0.78 PPARG (0.46) PPARAMAPTCYP2C19PPARGNPC1
Biphenyl SCHEMBL27873955 0.78 KIF11 (0.39) CYP1A2PPARACYP3A4MEN1KMT2A
SCHEMBL27362469 0.76 CHRNA7 (0.43) CYP1A2MEN1KMT2AMAPTCYP2C19
SCHEMBL93074 0.76 CA4 (0.48) CYP1A2PPARACYP3A4MEN1KMT2A
SCHEMBL198046 0.76 RIPK1 (0.43) CYP1A2PPARACYP3A4MEN1KMT2A
SCHEMBL10405698 0.76 CA4 (0.48) CYP1A2PPARACYP3A4MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8283104-B2 Sulfonate and its derivative, photosensitive acid generator, and resist composition and patterning process using the same SHIN-ETSU CHEMICAL CO., LTD. (JP) 2012-10-09 US disclosed
US-8202677-B2 Chemically-amplified positive resist composition and patterning process thereof SHIN-ETSU CHEMICAL CO., LTD. (JP) 2012-06-19 US disclosed
EP-2144116-B1 Chemically-amplified positive resist composition and patterning process using the same SHINETSU CHEMICAL CO (JP) 2011-11-02 EP disclosed
US-20100209827-A1 NOVEL SULFONATE AND ITS DERIVATIVE, PHOTOSENSITIVE ACID GENERATOR, AND RESIST COMPOSITION AND PATTERNING PROCESS USING THE SAME SHIN-ETSU CHEMICAL CO., LTD. (JP) 2010-08-19 US disclosed
US-20100009286-A1 Chemically-amplified positive resist composition and patterning process thereof SHIN-ETSU CHEMICAL CO., LTD. (JP) 2010-01-14 US disclosed
EP-2144116-A1 Chemically-amplified positive resist composition and patterning process thereof Shinetsu Chemical Co., Ltd. (JP) 2010-01-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100209827-A1 NOVEL SULFONATE AND ITS DERIVATIVE, PHOTOSENSITIVE ACID GENERATOR, AND RESIST COMPOSITION AND PATTERNING PROCESS USING THE SAME DAP3, MRPS23, ASIC3 CYP1A2 3322/4885PPARA 2808/4885CYP3A4 3672/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.