Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 9/20 | 0.62 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | HTR6 | P50406 | 7/20 | 0.47 |
| ▸ | CHKA | P35790 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 3/20 | 0.44 |
| ▸ | HTR1D | P28221 | 3/20 | 0.44 |
| ▸ | HTR1B | P28222 | 3/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.43 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.43 |
| ▸ | CDC42BPB | Q9Y5S2 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 2/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | HTR3A | P46098 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23726690 | 0.83 | NCF1 (0.90) | NCF1ADRB2HTR7HTR2BHTR3A | |
| SCHEMBL30080033 | 0.83 | NCF1 (0.90) | NCF1ADRB2HTR7HTR2BHTR3A | |
| SCHEMBL2594228 | 0.80 | NCF1 (0.90) | NCF1ADRB2PKMALOX15CASP1 | |
| SCHEMBL30061172 | 0.79 | NCF1 (0.70) | NCF1ADRB2PKMALOX15CASP1 | |
| SCHEMBL23412205 | 0.79 | NCF1 (0.88) | NCF1ADRB2PKMALOX15CASP1 | |
| SCHEMBL30060834 | 0.77 | NCF1 (0.64) | NCF1ADRB2PKMALOX15CASP1 | |
| SCHEMBL2587501 | 0.77 | NCF1 (0.90) | NCF1ADRB2PKMALOX15CASP1 | |
| SCHEMBL22441572 | 0.77 | NCF1 (1.00) | NCF1ADRB2HTR6ADRB1HTR3A | |
| SCHEMBL25656099 | 0.77 | CYP1A2 (0.56) | NCF1HSD17B10 | |
| SCHEMBL25656137 | 0.74 | ALDH1A1 (0.52) | NCF1PKMALOX15CASP1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230183212-A1 | INHIBITORS OF ECTONUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE 1 (ENPP1) AND METHODS OF USE THEREOF | STINGRAY THERAPEUTICS INC (US) | 2023-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230183212-A1 | INHIBITORS OF ECTONUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE 1 (ENPP1) AND METHODS OF USE THEREOF | ENPP1, ENPP3, PPA1 | NCF1 491/4885ADRB2 4189/4885PKM 2431/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.