Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.73 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.73 |
| ▸ | NPC1 | O15118 | 5/20 | 0.51 |
| ▸ | RAB9A | P51151 | 5/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | NAMPT | P43490 | 2/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzo[D]Thiazole SCHEMBL27590650 | 0.94 | ALDH1A1 (0.76) | ALDH1A1HSD17B10NPC1RAB9AKDM4E | |
| Benzo[D]Thiazole SCHEMBL27701795 | 0.94 | ALDH1A1 (0.76) | ALDH1A1HSD17B10NPC1RAB9AKDM4E | |
| Benzo[D]Thiazole SCHEMBL2329959 | 0.91 | ALDH1A1 (0.70) | ALDH1A1HSD17B10NPC1RAB9AKDM4E | |
| Benzo[D]Thiazole SCHEMBL11684233 | 0.90 | ALDH1A1 (0.76) | ALDH1A1HSD17B10NPC1RAB9AKDM4E | |
| Benzamide SCHEMBL17287741 | 0.90 | HSD17B10 (0.63) | ALDH1A1HSD17B10NPC1RAB9AKDM4E | |
| Benzo[D]Thiazole SCHEMBL10587301 | 0.89 | ALDH1A1 (0.73) | ALDH1A1HSD17B10NPC1RAB9AKDM4E | |
| Benzo[D]Thiazole SCHEMBL8169978 | 0.88 | ALDH1A1 (0.86) | ALDH1A1HSD17B10NPC1RAB9AKDM4E | |
| Benzo[D]Thiazole SCHEMBL2173015 | 0.88 | ALDH1A1 (0.95) | ALDH1A1HSD17B10NPC1RAB9AKDM4E | |
| Benzo[D]Thiazole SCHEMBL29049433 | 0.87 | ALDH1A1 (0.66) | ALDH1A1HSD17B10NPC1RAB9AKDM4E | |
| Benzo[D]Thiazole SCHEMBL27280438 | 0.87 | ALDH1A1 (0.66) | ALDH1A1HSD17B10NPC1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105295197-B | Method for regulating and controlling crystal form in iPP-EPDM rubber-plastic blended material by adopting double constant-temperature heating tables | 安徽大学 | 2017-06-13 | — | — | CN | claimed |
| WO-2011121223-A1 | 6-(ALKYL- OR CYCLOALKYL-TRIAZOLOPYRIDAZINE-SULFANYL) BENZOTHIAZOLE DERIVATIVES: PREPARATION, APPLICATION AS MEDICAMENTS AND USE AS MET INHIBITORS | SANOFI-AVENTIS (FR) | 2011-10-06 | — | — | WO | disclosed |