Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.76 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.76 |
| ▸ | NPC1 | O15118 | 7/20 | 0.49 |
| ▸ | RAB9A | P51151 | 7/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | NAMPT | P43490 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzo[D]Thiazole SCHEMBL2565700 | 0.94 | ALDH1A1 (0.73) | ALDH1A1HSD17B10NPC1RAB9AKDM4E | |
| Benzo[D]Thiazole SCHEMBL2329959 | 0.92 | ALDH1A1 (0.70) | ALDH1A1HSD17B10NPC1RAB9AKDM4E | |
| Benzo[D]Thiazole SCHEMBL8169978 | 0.90 | ALDH1A1 (0.86) | ALDH1A1HSD17B10NPC1RAB9AKDM4E | |
| Benzo[D]Thiazole SCHEMBL29049433 | 0.89 | ALDH1A1 (0.66) | ALDH1A1HSD17B10NPC1RAB9AKDM4E | |
| Benzo[D]Thiazole SCHEMBL11684233 | 0.88 | ALDH1A1 (0.76) | ALDH1A1HSD17B10NPC1RAB9AKDM4E | |
| Benzamide SCHEMBL17287741 | 0.88 | HSD17B10 (0.63) | ALDH1A1HSD17B10NPC1RAB9AKDM4E | |
| Benzo[D]Thiazole SCHEMBL29275430 | 0.88 | ALDH1A1 (0.63) | ALDH1A1HSD17B10NPC1RAB9AKDM4E | |
| Benzo[D]Thiazole SCHEMBL5308338 | 0.88 | ALDH1A1 (0.63) | ALDH1A1HSD17B10NPC1RAB9AKDM4E | |
| Benzo[D]Thiazole SCHEMBL451685 | 0.87 | — | — | |
| Benzo[D]Thiazole SCHEMBL8430 | 0.87 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100387636-C | Benzothiazole-carbamide polymer containing aliphatics lateral group and method for preparing the same | UNIV SHANGHAI JIAOTONG (CN) | 2008-05-14 | — | — | CN | disclosed |