Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.39 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.38 |
| ▸ | TTK | P33981 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2573254 | 0.78 | TTK (0.41) | KMT2AMEN1TDP1ROCK2L3MBTL1 | |
| SCHEMBL5665295 | 0.78 | BRPF1 (0.41) | KMT2AMEN1TDP1L3MBTL1MAPT | |
| SCHEMBL24638418 | 0.77 | CA12 (0.40) | ALDH1A1ACHE | |
| SCHEMBL30049939 | 0.77 | CA12 (0.40) | ALDH1A1ACHE | |
| SCHEMBL2565643 | 0.77 | TTK (0.45) | KMT2AMEN1TDP1ROCK2L3MBTL1 | |
| SCHEMBL14863509 | 0.76 | HTR1E (0.49) | KMT2AMEN1TDP1MAPTALDH1A1 | |
| SCHEMBL22890265 | 0.75 | LRRK2 (0.53) | — | |
| SCHEMBL29643913 | 0.75 | LRRK2 (0.53) | — | |
| SCHEMBL16125888 | 0.74 | CYP4F2 (0.39) | KMT2AMEN1L3MBTL1MAPTKDM4E | |
| SCHEMBL14863468 | 0.74 | NPY2R (0.40) | KMT2AMEN1MAPTALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011123937-A1 | KINASE INHIBITORS AND METHOD OF TREATING CANCER WITH SAME | UNIVERSITY HEALTH NETWORK (CA) | 2011-10-13 | — | — | WO | disclosed |
| WO-2011123937-A1 | KINASE INHIBITORS AND METHOD OF TREATING CANCER WITH SAME | UNIVERSITY HEALTH NETWORK (CA) | 2011-10-13 | — | — | WO | disclosed |