Sugi Predict

Sugi Predict / Compounds / SCHEMBL25660716

SCHEMBL25660716

SCHEMBL25660716

c1ccc(-c2ccccc2-c2nc(-c3ccc(-c4ccc5c(ccc6oc7ccccc7c65)c4)cc3)nc(-c3ccc4ccccc4c3)n2)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 5/20 0.39
▸ KDM4E B2RXH2 3/20 0.39
▸ CYP1A2 P05177 2/20 0.39
▸ HSD17B10 Q99714 2/20 0.39
▸ KMT2A Q03164 2/20 0.39
▸ MEN1 O00255 1/20 0.39
▸ TP53 P04637 1/20 0.39
▸ SMN1; SMN2 Q16637 1/20 0.39
▸ L3MBTL1 Q9Y468 2/20 0.36
▸ PGR P06401 1/20 0.36
▸ TDP1 Q9NUW8 1/20 0.36
▸ ABCG2 Q9UNQ0 2/20 0.36
▸ CYP1A1 P04798 1/20 0.36
▸ FYN P06241 1/20 0.36
▸ MAPK3 P27361 1/20 0.36
▸ AHR P35869 1/20 0.36
▸ PAX8 Q06710 1/20 0.36
▸ PLA2G2A P14555 1/20 0.36
▸ PLA2G4A P47712 1/20 0.36
▸ HSD17B1 P14061 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25660979 0.96 PGR (0.39) ALDH1A1KDM4ECYP1A2HSD17B10L3MBTL1
SCHEMBL25660701 0.95 ALDH1A1 (0.40) ALDH1A1KDM4ECYP1A2HSD17B10KMT2A
SCHEMBL22880376 0.94 TDP1 (0.38) ALDH1A1KDM4ECYP1A2HSD17B10KMT2A
SCHEMBL24372562 0.92 TDP1 (0.40) ALDH1A1KDM4ECYP1A2HSD17B10KMT2A
SCHEMBL25504090 0.91 ALDH1A1 (0.37) ALDH1A1KDM4ECYP1A2HSD17B10KMT2A
SCHEMBL25504187 0.91 ALDH1A1 (0.37) ALDH1A1KDM4ECYP1A2HSD17B10KMT2A
SCHEMBL23512128 0.91 ALDH1A1 (0.39) ALDH1A1KDM4ECYP1A2HSD17B10KMT2A
SCHEMBL24890017 0.91 ALDH1A1 (0.40) ALDH1A1KDM4ECYP1A2HSD17B10KMT2A
SCHEMBL25504480 0.91 TDP1 (0.38) ALDH1A1KDM4ECYP1A2HSD17B10KMT2A
SCHEMBL25504399 0.91 TDP1 (0.38) ALDH1A1KDM4ECYP1A2HSD17B10KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230371374-A1 PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2023-11-16 — — US disclosed
US-20230371374-A1 PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2023-11-16 — — US disclosed
US-20230157156-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD (KR) 2023-05-18 — — US disclosed
US-20230157156-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD (KR) 2023-05-18 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230371374-A1 PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME SOD1, TELO2, LIMS1 ALDH1A1 530/4885KDM4E 3228/4885CYP1A2 2142/4885
US-20230157156-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME OR10J3, VDAC2, ICOSLG ALDH1A1 604/4885KDM4E 892/4885CYP1A2 2132/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.