SCHEMBL256624

SCHEMBL256624

c1ccc(-n2cnnc2)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.52
CYP1A2 P05177 3/20 0.50
CYP2C9 P11712 3/20 0.50
TSHR P16473 2/20 0.48
MAPT P10636 1/20 0.48
QPCT Q16769 1/20 0.48
GABRG2 P18507 1/20 0.47
GABRB3 P28472 1/20 0.47
GABRA5 P31644 1/20 0.47
GABRA3 P34903 1/20 0.47
NOTUM Q6P988 1/20 0.46
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
ALOX15 P16050 1/20 0.40
KDM4E B2RXH2 1/20 0.40
HPGD P15428 1/20 0.40
HTT P42858 2/20 0.39
GAA P10253 1/20 0.39
ALDH1A1 P00352 1/20 0.37
PKM P14618 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29993530 0.97 CYP3A4 (0.50) CYP3A4CYP1A2CYP2C9TSHRMAPT
SCHEMBL29369633 0.83 CYP3A4 (0.43) CYP3A4CYP1A2CYP2C9TSHRMAPT
SCHEMBL7015795 0.79 CYP1A2 (0.59) CYP1A2CYP2C9TSHRQPCTMEN1
SCHEMBL7808697 0.79 ALDH1A1 (0.54) CYP3A4CYP1A2CYP2C9TSHRMAPT
SCHEMBL7013145 0.79 CYP1A2 (0.44) CYP3A4CYP1A2CYP2C9TSHRMAPT
SCHEMBL12841363 0.79 GABRG2 (0.68) CYP3A4CYP1A2CYP2C9TSHRMAPT
SCHEMBL11122638 0.72 CYP2A6 (0.64) CYP3A4CYP1A2HTTALDH1A1
SCHEMBL31440787 0.72 CYP2A6 (0.64) CYP3A4CYP1A2HTTALDH1A1
SCHEMBL1186988 0.72 ENPP2 (0.56) CYP3A4CYP1A2CYP2C9MAPTQPCT
SCHEMBL15555209 0.72 CYP1A2 (0.52) CYP1A2CYP2C9TSHRMAPTQPCT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2279 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240260429-A1 LIGHT EMITTING DISPLAY DEVICE LG DISPLAY CO., LTD (KR) 2024-08-01 US claimed
CN-118276422-A Low copper corrosion photoresist stripping liquid for ARRAY process 易安爱富(武汉)科技有限公司 2024-07-02 CN claimed
CN-116239787-A Three-dimensional coordination polymer with high proton conductivity and preparation method and application thereof 河南大学 2023-06-09 CN claimed
CN-112675154-B MOFs @ IBU nanofiber transdermal sustained-release material with double-response drug release and preparation method and application thereof 山东第一医科大学(山东省医学科学院) 2022-08-02 CN claimed
WO-2022143832-A1 OPTOELECTRONIC DEVICE TCL科技集团股份有限公司 2022-07-07 WO claimed
WO-2022143831-A1 OPTOELECTRONIC DEVICE TCL科技集团股份有限公司 2022-07-07 WO claimed
WO-2022143828-A1 PHOTOELECTRIC DEVICE TCL科技集团股份有限公司 2022-07-07 WO claimed
WO-2021202245-A1 VIRAL TREATMENT REGIMENS EGACEUTICAL CORPORATION (US) 2021-10-07 WO claimed
CN-106234385-A A kind of 1,2,4 triazole derivatives containing benzopyrazines structure are as the application of antibacterial 浙江工业大学 2016-12-21 CN claimed
US-4519940-A CONTAINING DOPED 1,3,4-TRIAZOLE RINGS CHEVRON RESEARCH COMPANY (US) 1985-05-28 US claimed
JP-7089813-A None JP disclosed
JP-7187919-A None JP disclosed
JP-7188220-A None JP disclosed
JP-7188221-A None JP disclosed
US-20260102379-A1 Inhibitor of PFKFB2 Kinase Activity and Cellular Glycolysis OKLAHOMA MED RES FOUND (US) 2026-04-16 US disclosed
JP-H07188221-A TRIAZOLE DERIVATIVE, HERBICIDE COMPOSITION FOR PADDY FIELD AND METHOD FOR USING THE SAME OTSUKA CHEM CO LTD 1995-07-25 JP disclosed
JP-H0789813-A HERBICIDE COMPOSITION FOR PADDY FIELD AND METHOD FOR USING THE SAME OTSUKA CHEM CO LTD 1995-04-04 JP disclosed
EP-0339841-A2 Photosensitive compositions and materials THE MEAD CORPORATION (US) 1989-11-02 EP disclosed
US-4519940-A CONTAINING DOPED 1,3,4-TRIAZOLE RINGS CHEVRON RESEARCH COMPANY (US) 1985-05-28 US disclosed
US-4087409-A USED TO SPIN FIBERS MONSANTO COMPANY (US) 1978-05-02 US disclosed