Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | POLB | P06746 | 2/20 | 0.59 |
| ▸ | RHOA | P61586 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | MAPK8 | P45983 | 4/20 | 0.54 |
| ▸ | MAPK10 | P53779 | 4/20 | 0.54 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | FAAH | O00519 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25668532 | 0.92 | KDM4E (0.63) | RAB9AALDH1A1POLBKDM4EMAPT | |
| SCHEMBL8363734 | 0.81 | PTPN1 (0.74) | RAB9AALDH1A1KDM4EMAPTNPC1 | |
| SCHEMBL1339196 | 0.79 | PTPN1 (0.71) | RAB9AALDH1A1KDM4EMAPTNPC1 | |
| SCHEMBL7863859 | 0.79 | PTPN1 (0.66) | RAB9AALDH1A1POLBKDM4EMAPT | |
| SCHEMBL21670498 | 0.79 | MEN1 (0.74) | RAB9AALDH1A1POLBKDM4ESMN1; SMN2 | |
| SCHEMBL17773265 | 0.78 | ALDH1A1 (0.61) | RAB9AALDH1A1POLBRHOAMAPT | |
| SCHEMBL18466528 | 0.78 | GFER (0.55) | — | |
| SCHEMBL25668713 | 0.77 | PKM (0.72) | RAB9AALDH1A1POLBKDM4EMAPT | |
| SCHEMBL17773259 | 0.76 | ALDH1A1 (0.61) | RAB9AALDH1A1POLBRHOASMN1; SMN2 | |
| SCHEMBL5554898 | 0.76 | RAB9A (0.72) | RAB9AALDH1A1POLBMAPK8MAPK10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023109883-A1 | AROMATIC HETEROCYCLE-SUBSTITUTED COMPOUNDS, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海翊石医药科技有限公司 | 2023-06-22 | — | — | WO | disclosed |