Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK5 | Q00535 | 2/20 | 0.46 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | RARB | P10826 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | SLC9A3 | P48764 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 4/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21787229 | 1.00 | CDK5 (0.46) | CDK5CDK5R1L3MBTL1BCHECNR2 | |
| SCHEMBL25493962 | 0.86 | L3MBTL1 (0.46) | L3MBTL1NPC1RAB9AKDM4ERARB | |
| SCHEMBL21125363 | 0.86 | L3MBTL1 (0.46) | L3MBTL1NPC1RAB9AKDM4ERARB | |
| SCHEMBL17721292 | 0.86 | RAB9A (0.47) | L3MBTL1NPC1RAB9AKDM4ECYP2C9 | |
| Hydrochloric Acid SCHEMBL21531561 | 0.84 | RAB9A (0.46) | L3MBTL1NPC1RAB9AKDM4ECYP2C9 | |
| SCHEMBL25897953 | 0.82 | RARB (0.45) | L3MBTL1NPC1RAB9AKDM4ERARB | |
| SCHEMBL25898026 | 0.82 | RARB (0.45) | L3MBTL1NPC1RAB9AKDM4ERARB | |
| SCHEMBL25427287 | 0.80 | L3MBTL1 (0.51) | L3MBTL1NPC1RAB9AKDM4ERARB | |
| SCHEMBL17721288 | 0.80 | L3MBTL1 (0.51) | L3MBTL1NPC1RAB9AKDM4ERARB | |
| SCHEMBL25623340 | 0.80 | L3MBTL1 (0.51) | L3MBTL1NPC1RAB9AKDM4ERARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024138000-A1 | PRODRUGS OF TOPOISOMERASE I INHIBITOR FOR ADC CONJUGATIONS AND METHODS OF USE THEREOF | REGENERON PHARMACEUTICALS, INC. (US) | 2024-06-27 | — | — | WO | disclosed |
| US-20230364262-A1 | VIA CYCLOADDITION BILATERALLY FUNCTIONALIZED ANTIBODIES | SYNAFFIX B.V. (NL) | 2023-11-16 | — | — | US | disclosed |
| US-20230190951-A1 | CONJUGATES OF ANTIBODIES AN IMMUNE CELL ENGAGERS | SYNAFFIX B.V. (NL) | 2023-06-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230190951-A1 | CONJUGATES OF ANTIBODIES AN IMMUNE CELL ENGAGERS | FCGR3B, FCGR1A, FCGR2A | CDK5 4572/4885CDK5R1 3482/4885L3MBTL1 2703/4885 |
| US-20230364262-A1 | VIA CYCLOADDITION BILATERALLY FUNCTIONALIZED ANTIBODIES | FCGR1A, FCGR3B, FCGR2A | CDK5 2743/4885CDK5R1 2307/4885L3MBTL1 117/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.