SCHEMBL2567290

SCHEMBL2567290

COCCNCc1ccncc1

nearest known ligand 0.57

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.57
ALDH1A1 P00352 3/20 0.54
KDM4E B2RXH2 1/20 0.54
GLA P06280 1/20 0.54
NAMPT P43490 3/20 0.52
GAA P10253 1/20 0.50
BRAF P15056 1/20 0.49
HTR2A P28223 1/20 0.49
HTR2C P28335 1/20 0.49
TBK1 Q9UHD2 1/20 0.47
CYP3A4 P08684 2/20 0.45
CYP2D6 P10635 2/20 0.45
HTT P42858 1/20 0.44
CYP2C19 P33261 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.42
SLC2A4 P14672 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29444840 0.81 MEN1 (0.56) ALDH1A1KDM4EGLAGAAHTR2A
SCHEMBL5227100 0.80 ALDH1A1 (0.47) L3MBTL1ALDH1A1KDM4EGLANAMPT
SCHEMBL556793 0.80 MEN1 (0.64) L3MBTL1GAA
SCHEMBL5113242 0.79 CYP1A2 (0.65) ALDH1A1GAAHTR2AHTR2CCYP2D6
SCHEMBL8252520 0.78 L3MBTL1 (0.64) L3MBTL1ALDH1A1KDM4EHTTSMN1; SMN2
SCHEMBL12317 0.78 L3MBTL1 (0.64) L3MBTL1ALDH1A1HTR2AHTT
Hydrochloric Acid SCHEMBL30321036 0.78 L3MBTL1 (0.64) L3MBTL1GAAHTT
SCHEMBL3741348 0.78 ALDH1A1 (0.50) ALDH1A1KDM4EGLANAMPTGAA
SCHEMBL11711163 0.77 HTR1A (0.58) ALDH1A1KDM4EGLAGAAHTR2A
SCHEMBL1241301 0.77 L3MBTL1 (0.62) L3MBTL1ALDH1A1KDM4EGLAGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2382274-B1 AQUEOUS COATING COMPOSITION COMPRISING PYRIDINE GROUP-CONTAINING ELECTROCOAT RESIN BASF COATINGS GMBH (DE) 2015-04-22 EP disclosed
CN-102272246-B Pyridine group-containing electrocoat resin BASF COATINGS GMBH 2014-09-17 CN disclosed
CN-102272246-A Pyridine group-containing electrocoat resin 2011-12-07 CN disclosed
EP-2382274-A1 PYRIDINE GROUP-CONTAINING ELECTROCOAT RESIN BASF Coatings GmbH (DE) 2011-11-02 EP disclosed
WO-2010077404-A1 PYRIDINE GROUP-CONTAINING ELECTROCOAT RESIN BASF COATINGS GMBH (US) 2010-07-08 WO disclosed
US-20100167069-A1 PYRIDINE GROUP-CONTAINING ELECTROCOAT RESIN BASF CORPORATION (US) 2010-07-01 US disclosed
US-20100167071-A1 PYRIDINE GROUP-CONTAINING ELECTROCOAT COMPOSITION WITH METAL OXIDE BASF CORPORATION (US) 2010-07-01 US disclosed
EP-1654257-B1 AMINOPYRONES AND THEIR USE AS ATM INHIBITORS KUDOS PHARM LTD (GB) 2010-03-17 EP disclosed