SCHEMBL25673189

SCHEMBL25673189

CC(=O)C[C@@H](C)c1c(O)ncnc1O

nearest known ligand 0.38

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
BRD4 O60885 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25209479 0.85 FFAR1 (0.38) ALDH1A1L3MBTL1
SCHEMBL16773713 0.79 ALDH1A1 (0.37) ALDH1A1TDP1
SCHEMBL10550129 0.67 ALDH1A1 (0.39) ALDH1A1TDP1
SCHEMBL7502585 0.64 PTGS2 (0.32) ALDH1A1
SCHEMBL28957054 0.64 FFAR1 (0.37) ALDH1A1L3MBTL1
SCHEMBL28957053 0.64 FFAR1 (0.37) ALDH1A1L3MBTL1
SCHEMBL25265377 0.64 FFAR1 (0.37) ALDH1A1L3MBTL1
SCHEMBL10241629 0.64 ESR1 (0.53) ALDH1A1TDP1
SCHEMBL16229539 0.63 L3MBTL1 (0.34) ALDH1A1L3MBTL1
SCHEMBL28612749 0.61 TBXAS1 (0.36) L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023109540-A1 HETEROCYCLIC COMPOUND WITH AKT KINASE INHIBITORY ACTIVITY, PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF 中国医药研究开发中心有限公司 2023-06-22 WO disclosed