SCHEMBL2567368

SCHEMBL2567368

Cc1cc(S(=O)(=O)O)cs1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DAO P14920 2/20 0.43
HPGD P15428 2/20 0.38
MAPK1 P28482 1/20 0.38
ALDH1A1 P00352 4/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
KMT2A Q03164 2/20 0.36
USP2 O75604 1/20 0.36
TSHR P16473 3/20 0.36
LCK P06239 1/20 0.35
FYN P06241 1/20 0.35
LMNA P02545 1/20 0.34
ING2 Q9H160 1/20 0.34
TDP1 Q9NUW8 3/20 0.33
HSD17B10 Q99714 2/20 0.33
CA2 P00918 1/20 0.33
SNCA P37840 1/20 0.33
NT5E P21589 1/20 0.33
NPC1 O15118 1/20 0.32
RAB9A P51151 1/20 0.32
NPSR1 Q6W5P4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2173431 0.98 DAO (0.42) DAOHPGDMAPK1ALDH1A1SMN1; SMN2
SCHEMBL16288940 0.79 DAO (0.40) DAOHPGDMAPK1ALDH1A1SMN1; SMN2
SCHEMBL2007922 0.77 CA2 (0.44) DAOALDH1A1CA2
SCHEMBL11475698 0.77 DAO (0.39) DAOHPGDMAPK1ALDH1A1SMN1; SMN2
Lithium Ion SCHEMBL2173434 0.76 LMNA (0.42) DAOHPGDMAPK1ALDH1A1SMN1; SMN2
SCHEMBL23569072 0.74 CA2 (0.39) DAOCA2
SCHEMBL7193262 0.73 TSHR (0.36) ALDH1A1SMN1; SMN2TSHRLCKFYN
SCHEMBL18701537 0.73 TSHR (0.36) ALDH1A1SMN1; SMN2KMT2ATSHRLCK
SCHEMBL5355039 0.73 DAO (0.43) DAOALDH1A1SMN1; SMN2KMT2ATSHR
Hydrochloric Acid SCHEMBL28047347 0.72 CA2 (0.38) SMN1; SMN2TSHRLCKFYNCA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2382190-A1 TOLUIDINE SULFONAMIDES AND THEIR USE AS-INHIBITORS European Molecular Biology Laboratory (EMBL) (DE) 2011-11-02 EP disclosed
WO-2010085968-A1 TOLUIDINE SULFONAMIDES AND THEIR USE AS HIF-INHIBITORS EUROPEAN MOLECULAR BIOLOGY LABORATORY (EMBL) (DE) 2010-08-05 WO disclosed
WO-2010076034-A1 TOLUIDINE SULFONAMIDES AND THEIR USE AS-INHIBITORS EUROPEAN MOLECULAR BIOLOGY LABORATORY (EMBL) (DE) 2010-07-08 WO disclosed