SCHEMBL11475698

SCHEMBL11475698

Cc1cc(S(=O)(=O)Cl)cs1

nearest known ligand 0.39

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
DAO P14920 1/20 0.39
ALDH1A1 P00352 2/20 0.36
HSD17B10 Q99714 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
CA2 P00918 1/20 0.33
HPGD P15428 1/20 0.31
MAPK1 P28482 1/20 0.31
USP2 O75604 1/20 0.31
KMT2A Q03164 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16288940 0.79 DAO (0.40) DAOALDH1A1CA2HPGDMAPK1
SCHEMBL2567368 0.77 DAO (0.43) DAOALDH1A1HSD17B10TDP1CA2
SCHEMBL2007922 0.77 CA2 (0.44) DAOALDH1A1CA2
Lithium Ion SCHEMBL2173434 0.76 LMNA (0.42) DAOALDH1A1TDP1CA2HPGD
SCHEMBL2173431 0.76 DAO (0.42) DAOALDH1A1HSD17B10TDP1CA2
SCHEMBL4875871 0.74 ALDH1A1 (0.42) DAOALDH1A1HSD17B10TDP1
SCHEMBL23569072 0.74 CA2 (0.39) DAOCA2
SCHEMBL15880882 0.74 CA2 (0.39) ALDH1A1HSD17B10TDP1CA2
SCHEMBL28199444 0.73 ALDH1A1 (0.36) ALDH1A1HSD17B10TDP1
SCHEMBL8493663 0.71 HTR6 (0.54) DAOALDH1A1CA2KMT2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025262003-A1 DIHYDRO BENZOXAZINE DERIVATIVES F. HOFFMANN-LA ROCHE AG (CH) 2025-12-26 WO disclosed
US-4237130-A DIURETICS, HYPOTENSIVE AGENTS MERCK & CO., INC. (US) 1980-12-02 US disclosed