Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | CIT | O14578 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | METAP2 | P50579 | 1/20 | 0.41 |
| ▸ | METAP1 | P53582 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2570332 | 0.79 | KDM4E (0.47) | AAK1SMN1; SMN2HPGDNPC1RAB9A | |
| SCHEMBL13069897 | 0.79 | PPM1D (0.41) | SMN1; SMN2HPGDNPC1RAB9ACYP1A2 | |
| SCHEMBL8252759 | 0.78 | F10 (0.45) | — | |
| SCHEMBL2571662 | 0.78 | F10 (0.45) | — | |
| SCHEMBL2573167 | 0.78 | ALOX15 (0.44) | SMN1; SMN2HPGDNPC1RAB9AALOX15 | |
| SCHEMBL2569655 | 0.78 | HPGD (0.41) | SMN1; SMN2HPGDNPC1RAB9ACYP3A4 | |
| SCHEMBL2567550 | 0.77 | POLB (0.46) | SMN1; SMN2HPGDNPC1RAB9AALOX15 | |
| SCHEMBL2563694 | 0.77 | ALOX15 (0.43) | AAK1SMN1; SMN2HPGDRAB9ACYP3A4 | |
| SCHEMBL2571876 | 0.77 | ROCK2 (0.48) | AAK1NPC1RAB9AALDH1A1KMT2A | |
| SCHEMBL2570020 | 0.77 | KDM4E (0.48) | AAK1HPGDNPC1RAB9ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1899330-B9 | SUBSTITUTED GLYCINAMIDES HAVING AN ANTITHROMBOTIC AND FACTOR XA-INHIBITING EFFECT | BOEHRINGER INGELHEIM INT (DE) | 2011-11-09 | — | — | EP | claimed |
| EP-1899330-B1 | SUBSTITUTED GLYCINAMIDES HAVING AN ANTITHROMBOTIC AND FACTOR XA-INHIBITING EFFECT | BOEHRINGER INGELHEIM INT (DE) | 2010-11-24 | — | — | EP | claimed |