Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 2/20 | 0.64 |
| ▸ | CES2 | O00748 | 1/20 | 0.64 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.54 |
| ▸ | FNTA | P49354 | 1/20 | 0.52 |
| ▸ | FNTB | P49356 | 1/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.50 |
| ▸ | PAM | P19021 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3506116 | 0.86 | LMNA (0.69) | CES1CES2AKR1B1MEN1KMT2A | |
| SCHEMBL11212239 | 0.82 | CA2 (0.62) | AKR1B1MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL6156467 | 0.81 | ALOX5 (0.65) | HDAC6LMNAPTGS1 | |
| SCHEMBL77563 | 0.78 | CES1 (0.70) | CES1CES2AKR1B1MEN1KMT2A | |
| Phenylacetic Acid SCHEMBL9449909 | 0.78 | AKR1B1 (1.00) | CES1CES2AKR1B1MEN1KMT2A | |
| Phenylacetic Acid SCHEMBL1459 | 0.78 | AKR1B1 (1.00) | CES1CES2AKR1B1MEN1KMT2A | |
| Phenylacetic Acid SCHEMBL1330777 | 0.78 | AKR1B1 (1.00) | CES1CES2AKR1B1MEN1KMT2A | |
| Phenylacetic Acid SCHEMBL13618842 | 0.78 | AKR1B1 (1.00) | CES1CES2AKR1B1MEN1KMT2A | |
| SCHEMBL574185 | 0.78 | CES1 (1.00) | CES1CES2AKR1B1MEN1KMT2A | |
| Phenylacetic Acid SCHEMBL27758886 | 0.78 | AKR1B1 (1.00) | CES1CES2AKR1B1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 4732 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113563365-B | Preparation method of 7-amino-3-methoxy-4-cephalosporanic acid | 华中药业股份有限公司 | 2024-05-28 | — | — | CN | claimed |
| WO-2024068519-A1 | 3-(HETERO)ARYL-5-CHLORODIFLUOROMETHYL-1,2,4-OXADIAZOLE AS FUNGICIDE | BAYER AKTIENGESELLSCHAFT (DE) | 2024-04-04 | — | — | WO | claimed |
| WO-2024068520-A1 | 3-(HETERO)ARYL-5-CHLORODIFLUOROMETHYL-1,2,4-OXADIAZOLE AS FUNGICIDE | BAYER AKTIENGESELLSCHAFT (DE) | 2024-04-04 | — | — | WO | claimed |
| CN-116589482-A | Metal beta-lactamase fluorescent probe and preparation method and application thereof | 南京工业大学 | 2023-08-15 | — | — | CN | claimed |
| EP-3500570-B1 | 5-HT2C RECEPTOR AGONISTS AND COMPOSITIONS AND METHODS OF USE | ARENA PHARM INC (US) | 2022-10-05 | — | — | EP | claimed |
| CN-113416200-B | Bistable electrochromic fluoran dye and preparation method of device thereof | 江南大学 | 2022-08-02 | — | — | CN | claimed |
| CN-111718361-B | Metal beta-lactamase inhibitor and preparation method and application thereof | 南京工业大学 | 2022-04-05 | — | — | CN | claimed |
| CN-109952301-B | 5-HT2C receptor agonists and compositions and methods of use | 艾尼纳制药公司 | 2022-03-25 | — | — | CN | claimed |
| US-10836764-B2 | 5-HT2C receptor agonists and compositions and methods of use | ARENA PHARMACEUTICALS, INC. (US) | 2020-11-17 | — | — | US | claimed |
| CN-111718361-A | Metal beta-lactamase inhibitor and preparation method and application thereof | 南京工业大学 | 2020-09-29 | — | — | CN | claimed |
| US-4042585-A | Process for preparation of 3-halomethylcephems | ELI LILLY AND COMPANY (US) | 1977-08-16 | — | — | US | claimed |
| US-4038275-A | PROCESS FOR PREPARATION OF 3-HYDROXYMETHYLCEPHEMS | ELI LILLY AND COMPANY (US) | 1977-07-26 | — | — | US | claimed |
| US-4031084-A | Process for cephalosporin antibiotic intermediates | ELI LILLY AND COMPANY (US) | 1977-06-21 | — | — | US | claimed |
| US-4022773-A | 7-ACYLAMINO-3-SUBSTITUTED-3-CEPHEM-4-CARBOXYLIC ACIDS, 1-OXIDES | ISHIMARU TOSHIYASU | 1977-05-10 | — | — | US | claimed |
| US-4014892-A | ANTHELMINTICS | AMERICAN CYANAMID COMPANY (US) | 1977-03-29 | — | — | US | claimed |
| US-4009159-A | PENICILLINS | FUJISAWA PHARMACEUTICAL CO., LTD. (JA) | 1977-02-22 | — | — | US | claimed |
| US-3989685-A | FROM PENICILLIN-1-OXIDE | SHINOGI & CO., LTD. (JA) | 1976-11-02 | — | — | US | claimed |
| US-3954732-A | BACTERICIDAL PENICILLINS | FUJISAWA PHARMACEUTICAL CO., LTD. (JA) | 1976-05-04 | — | — | US | claimed |
| US-3951951-A | Azetidinones | BEECHAM GROUP LIMITED (EN) | 1976-04-20 | — | — | US | claimed |
| US-3950347-A | NAPHTHOLACTAM DYESTUFFS | BAYER AKTIENGESELLSCHAFT (DT) | 1976-04-13 | — | — | US | claimed |