Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB5 | P28074 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | STAT3 | P40763 | 1/20 | 0.34 |
| ▸ | TERT | O14746 | 1/20 | 0.33 |
| ▸ | MBNL1 | Q9NR56 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | NQO2 | P16083 | 1/20 | 0.31 |
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL862359 | 0.78 | MEN1 (0.56) | PSMB5MEN1KMT2AKDM4ETDP1 | |
| SCHEMBL8643542 | 0.75 | ALDH1A1 (0.49) | MEN1KMT2APDE10AKDM4EMAPT | |
| SCHEMBL27910453 | 0.75 | TTR (0.46) | MEN1KMT2APDE10AKDM4ETDP1 | |
| SCHEMBL12827021 | 0.75 | TSHR (0.51) | MEN1KMT2APDE10AKDM4EMAPT | |
| SCHEMBL12500744 | 0.75 | KDM4E (0.57) | MEN1KMT2APDE10AKDM4EMAPT | |
| SCHEMBL12597248 | 0.72 | CYP1A2 (0.63) | MEN1KMT2AKDM4ECYP1A2 | |
| SCHEMBL9797601 | 0.72 | TERT (0.46) | MEN1KMT2APDE10AKDM4ETDP1 | |
| SCHEMBL13238155 | 0.72 | KDM4E (0.59) | MEN1KMT2AKDM4EMAPTALDH1A1 | |
| SCHEMBL12231918 | 0.72 | PSMB5 (0.52) | PSMB5MEN1KMT2APDE10AKDM4E | |
| SCHEMBL422035 | 0.71 | ALDH1A1 (0.63) | MEN1KMT2APDE10AKDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11685737-B2 | Fluorinated integrin antagonists | OCUTERRA THERAPEUTICS, INC. (US) | 2023-06-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11685737-B2 | Fluorinated integrin antagonists | ITGB5, ITGB1, ITGA5 | PSMB5 2023/4885MEN1 3906/4885KMT2A 4143/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.