SCHEMBL9797601

SCHEMBL9797601

Cc1cc2cc(C)c(C)nc2cc1C

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TERT O14746 1/20 0.46
CYP1A2 P05177 3/20 0.45
CYP3A4 P08684 3/20 0.45
CYP2D6 P10635 1/20 0.45
CYP2C19 P33261 1/20 0.45
NQO2 P16083 1/20 0.44
PDE3B Q13370 1/20 0.44
PDE3A Q14432 1/20 0.44
MAPT P10636 5/20 0.42
GAA P10253 3/20 0.42
RAB9A P51151 2/20 0.42
POLB P06746 1/20 0.42
KDM4E B2RXH2 6/20 0.42
ALDH1A1 P00352 5/20 0.42
SMN1; SMN2 Q16637 3/20 0.42
GLA P06280 1/20 0.42
HPGD P15428 1/20 0.42
BCAT2 O15382 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
HSD17B10 Q99714 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9755344 0.82 TERT (0.64) TERTCYP1A2CYP3A4CYP2D6CYP2C19
SCHEMBL15119521 0.80 KDM4E (0.55) TERTCYP1A2CYP3A4CYP2D6CYP2C19
SCHEMBL13156604 0.80 NQO2 (0.59) TERTCYP1A2CYP3A4CYP2D6CYP2C19
SCHEMBL2490986 0.79 NQO2 (0.57) CYP3A4NQO2MAPTGAARAB9A
SCHEMBL8353234 0.77 GRM1 (0.44) CYP1A2CYP3A4CYP2D6CYP2C19PDE3B
SCHEMBL12728407 0.75 KDM4E (0.48) TERTCYP1A2CYP3A4CYP2D6CYP2C19
SCHEMBL862359 0.75 MEN1 (0.56) CYP1A2NQO2PDE3BPDE3AMAPT
SCHEMBL862486 0.75 ALDH1A1 (0.56) CYP1A2NQO2MAPTGAAPOLB
SCHEMBL9308885 0.74 MEN1 (0.54) KDM4EALDH1A1SMN1; SMN2BCAT2MEN1
SCHEMBL25666462 0.74 TERT (0.35) TERT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2880080-B1 POLYMERS, POLYMER MEMBRANES AND METHODS OF PRODUCING THE SAME AIR PROD & CHEM (US) 2018-07-04 EP disclosed
US-9396831-B2 Polymer compound and electronic device using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-07-19 US disclosed
US-9396831-B2 Polymer compound and electronic device using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-07-19 US disclosed
US-8753426-B2 Polymers, polymer membranes and methods of producing the same AIR PRODUCTS AND CHEMICALS, INC. (US) 2014-06-17 US disclosed
US-20140084217-A1 POLYMER COMPOUND AND ELECTRONIC DEVICE USING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-03-27 US disclosed
US-20140084217-A1 POLYMER COMPOUND AND ELECTRONIC DEVICE USING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-03-27 US disclosed
US-20140033918-A1 Polymers, Polymer Membranes And Methods Of Producing The Same AIR PRODUCTS AND CHEMICALS, INC. (US) 2014-02-06 US disclosed
US-20140033918-A1 Polymers, Polymer Membranes And Methods Of Producing The Same AIR PRODUCTS AND CHEMICALS, INC. (US) 2014-02-06 US disclosed
WO-2014022738-A1 POLYMERS, POLYMER MEMBRANES AND METHODS OF PRODUCING THE SAME AIR PRODUCTS AND CHEMICALS, INC. (US) 2014-02-06 WO disclosed
US-7652124-B2 Rigid heterocyclic polymer, production process thereof, and fibers comprising the polymer TEIJIN LIMITED (JP) 2010-01-26 US disclosed
US-4981978-A Reaction products of imidazole on pyrazole derivatives and 4-isopropenyl-1-cyclohexene-1-carboxaldehyde THE DOW CHEMICAL COMPANY (US) 1991-01-01 US disclosed
US-4927932-A Reaction products of pyrimidine, pyridazine and 4-isopropenyl-1-cyclohexene-1-carboxaldehyde THE DOW CHEMICAL COMPANY (US) 1990-05-22 US disclosed
US-4831137-A Reaction products of pteridine and 4-isopropenyl-1-cyclohexene-1-carboxaldehyde THE DOW CHEMICAL COMPANY (US) 1989-05-16 US disclosed
US-4755600-A Reaction products of pyrazine, pyridine, quinoline and quinoxaline derivatives and 4-isopropenyl-1-cyclohexene-1-carboxaldehyde THE DOW CHEMICAL COMPANY (US) 1988-07-05 US disclosed
US-4680347-A Thermosettable polystyrylpyrazine polymers terminated with ethylenically unsaturated groups and cured products therefrom THE DOW CHEMICAL COMPANY (US) 1987-07-14 US disclosed
EP-0202244-A4 CURED PRODUCTS FROM THERMOSETTABLE POLYMERS OR PREPOLYMERS PREPARED FROM POLYMETHYLATED PYRAZINES AND AROMATIC POLYALDEHYDES. DOW CHEMICAL CO (US) 1987-04-28 EP disclosed
US-4629770-A Thermosettable polystyrylpyrazine polymers terminated with ethylenically unsaturated groups and cured products therefrom THE DOW CHEMICAL COMPANY (US) 1986-12-16 US disclosed
EP-0202244-A1 CURED PRODUCTS FROM THERMOSETTABLE POLYMERS OR PREPOLYMERS PREPARED FROM POLYMETHYLATED PYRAZINES AND AROMATIC POLYALDEHYDES. DOW CHEMICAL CO (US) 1986-11-26 EP disclosed
WO-1986002932-A1 THERMOSETTABLE POLYMERS OR PREPOLYMERS PREPARED FROM POLYMETHYLATED PYRAZINES AND AROMATIC POLYALDEHYDES AND CURED PRODUCTS THEREFROM THE DOW CHEMICAL COMPANY (US) 1986-05-22 WO disclosed
US-4543388-A Thermosettable polymers or prepolymers prepared from polymethylated pyrazines and aromatic polyaldehydes and cured products therefrom THE DOW CHEMICAL COMPANY (US) 1985-09-24 US disclosed