Sugi Predict

Sugi Predict / Compounds / SCHEMBL256755

SCHEMBL256755

SCHEMBL256755

CCOC(=O)c1ccnc(N)c1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ GABRP O00591 1/20 0.56
▸ GABRD O14764 1/20 0.56
▸ GABRA1 P14867 1/20 0.56
▸ GABRB1 P18505 1/20 0.56
▸ GABRG2 P18507 1/20 0.56
▸ GABRB3 P28472 1/20 0.56
▸ GABRA5 P31644 1/20 0.56
▸ GABRA3 P34903 1/20 0.56
▸ GABRA2 P47869 1/20 0.56
▸ GABRB2 P47870 1/20 0.56
▸ GABRA4 P48169 1/20 0.56
▸ GABRE P78334 1/20 0.56
▸ GABRA6 Q16445 1/20 0.56
▸ GABRG1 Q8N1C3 1/20 0.56
▸ GABRG3 Q99928 1/20 0.56
▸ GABRQ Q9UN88 1/20 0.56
▸ JMJD6 Q6NYC1 4/20 0.56
▸ LMNA P02545 1/20 0.54
▸ CYP1A2 P05177 1/20 0.54
▸ CYP3A4 P08684 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL5591077 0.98 JMJD6 (0.55) GABRPGABRDGABRA1GABRB1GABRG2
Hydrochloric Acid SCHEMBL6740832 0.98 JMJD6 (0.55) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL811785 0.83 JMJD6 (0.76) JMJD6PIK3CACA12CA1CA2
SCHEMBL363249 0.83 JMJD6 (0.58) JMJD6LMNACYP1A2CYP3A4MAOA
SCHEMBL30171421 0.83 JMJD6 (0.76) JMJD6PIK3CACA12CA1CA2
SCHEMBL930636 0.81 JMJD6 (0.57) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL6500351 0.81 JMJD6 (0.57) JMJD6LMNACYP1A2CYP3A4MAOA
SCHEMBL29466587 0.81 JMJD6 (0.57) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL339851 0.81 GABRP (0.61) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL29437205 0.81 GABRP (0.61) GABRPGABRDGABRA1GABRB1GABRG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 231 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118638538-A Cleanup additive for oilfield acidizing and fracturing and preparation method thereof 寿光新海能源技术有限公司 2024-09-13 — — CN claimed
US-20240154124-A1 NEGATIVE ELECTRODE PLATE AND LITHIUM-ION BATTERY COMPRISING SAME ZHUHAI COSMX BATTERY CO., LTD. (CN) 2024-05-09 — — US claimed
CN-109134361-A A kind of synthetic method of intermediate 2-amino pyridine-4-formic acid ethyl ester 苏州盖德精细材料有限公司 2019-01-04 — — CN claimed
CN-120987645-B Tundish composite coating for clean steel and preparation method thereof 河北国亮新材料股份有限公司 2026-01-23 — — CN disclosed
CN-120987645-A Tundish composite coating for clean steel and preparation method thereof 河北国亮新材料股份有限公司 2025-11-21 — — CN disclosed
WO-2025128848-A1 HETEROCYCLIC COMPOUNDS AS TRIGGERING RECEPTOR EXPRESSED ON MYELOID CELLS 2 AGONISTS AND METHODS OF USE VIGIL NEUROSCIENCE, INC. (US) 2025-06-19 — — WO disclosed
US-20250136607-A1 PAD4 INHIBITORS AND USE THEREOF REGOR PHARMACEUTICALS, INC. 2025-05-01 — — US disclosed
CN-116120313-B Pyridoimidazole nitrogen fused ring compound and preparation method and application thereof 遵义医科大学 2025-02-11 — — CN disclosed
EP-4433477-A1 PAD4 INHIBITORS AND USE THEREOF Regor Pharmaceuticals, Inc. (US) 2024-09-25 — — EP disclosed
CN-118679162-A PAD4 inhibitors and uses thereof 锐格药业公司 2024-09-20 — — CN disclosed
CN-118638538-A Cleanup additive for oilfield acidizing and fracturing and preparation method thereof 寿光新海能源技术有限公司 2024-09-13 — — CN disclosed
EP-0685470-A2 Benzene derivatives and pharmaceutical composition Kureha Chemical Industry Co., Ltd. (JP) 1995-12-06 — — EP disclosed
US-4291036-A Pyrido[1,2-A]pyrimidine derivatives and method of analgesic treatment CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA RT. (HU) 1981-09-22 — — US disclosed
US-4219649-A ANALGESICS CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA RT (HU) 1980-08-26 — — US disclosed
US-4101583-A Alpha-methylthio-alpha-(2-aminophenyl) acetaldehyde diloweralkyl acetals THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) 1978-07-18 — — US disclosed
US-4080341-A Carbazolenine and indole compounds THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) 1978-03-21 — — US disclosed
US-4067875-A Certain N-phenyl or N-pyridyl aza sulfonium salts THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) 1978-01-10 — — US disclosed
US-4035375-A N-Substituted amino pyridines and derivatives thereof THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) 1977-07-12 — — US disclosed
US-3992392-A Synthesis of indoles from anilines and intermediates therein THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) 1976-11-16 — — US disclosed
US-3985756-A Process for producing azasulfonium salts and rearrangement thereof to thio-ethers THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) 1976-10-12 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250136607-A1 PAD4 INHIBITORS AND USE THEREOF PADI4, PADI6, PADI2 GABRP 1932/4885GABRD 3233/4885GABRA1 3559/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.