Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 5/20 | 0.55 |
| ▸ | TAAR1 | Q96RJ0 | 5/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.39 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL759880 | 0.81 | TAAR1 (0.61) | TRPA1TAAR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL873143 | 0.81 | TAAR1 (0.61) | TRPA1TAAR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL9908239 | 0.81 | TAAR1 (0.61) | TRPA1TAAR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL1911102 | 0.77 | TRPA1 (0.65) | TRPA1TAAR1SLC6A2SIGMAR1MAOA | |
| SCHEMBL94629 | 0.77 | TRPA1 (0.65) | TRPA1TAAR1SLC6A2SIGMAR1MAOA | |
| SCHEMBL358058 | 0.77 | TRPA1 (0.65) | TRPA1TAAR1SLC6A2SIGMAR1MAOA | |
| SCHEMBL4785594 | 0.77 | SIGMAR1 (0.64) | TRPA1TAAR1SLC6A2SIGMAR1MAOA | |
| SCHEMBL9186461 | 0.75 | TAAR1 (0.59) | TRPA1TAAR1SLC6A2SIGMAR1MAOA | |
| SCHEMBL8365210 | 0.74 | ACP3 (0.50) | TRPA1TAAR1SLC6A2SIGMAR1MAOA | |
| SCHEMBL28452098 | 0.74 | TAAR1 (0.57) | TRPA1TAAR1SLC6A2SIGMAR1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11730810-B2 | Composition comprising an antigen and a substituted imidazo[1,2-a]pyrimidine for enhancing human immune response | CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2023-08-22 | — | — | US | disclosed |
| US-11673891-B2 | Imidazopyrimidine compounds and uses thereof | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2023-06-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11730810-B2 | Composition comprising an antigen and a substituted imidazo[1,2-a]pyrimidine for enhancing human immune response | CD4, MYD88, STING1 | TRPA1 3270/4885TAAR1 3449/4885ALOX5 2815/4885 |
| US-11673891-B2 | Imidazopyrimidine compounds and uses thereof | HLA-DRB1, HLA-A, IRF3 | TRPA1 1438/4885TAAR1 3639/4885ALOX5 589/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.