Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.35 |
| ▸ | GFER | P55789 | 2/20 | 0.35 |
| ▸ | ALPL | P05186 | 1/20 | 0.35 |
| ▸ | ALPI | P09923 | 1/20 | 0.35 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ABCC8 | Q09428 | 5/20 | 0.35 |
| ▸ | KCNJ11 | Q14654 | 5/20 | 0.35 |
| ▸ | IGF1R | P08069 | 1/20 | 0.34 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1872522 | 0.85 | ALDH1A1 (0.44) | MEN1KMT2ANPC1RAB9APAX8 | |
| SCHEMBL4519825 | 0.74 | CTSB (0.40) | MEN1KMT2APOLBGFERALPL | |
| SCHEMBL30594978 | 0.74 | CTSB (0.40) | MEN1KMT2APOLBGFERALPL | |
| SCHEMBL31202669 | 0.73 | GPR35 (0.41) | MEN1KMT2ANPC1RAB9APAX8 | |
| SCHEMBL8743905 | 0.73 | GPR35 (0.41) | MEN1KMT2ANPC1RAB9APAX8 | |
| SCHEMBL1759447 | 0.72 | MEN1 (0.37) | MEN1KMT2APOLBGFERALPL | |
| SCHEMBL1867497 | 0.72 | FABP4 (0.50) | MEN1KMT2APOLBIGF1RALDH1A1 | |
| SCHEMBL18188110 | 0.70 | ALDH1A1 (0.47) | MEN1KMT2ANPC1RAB9APAX8 | |
| SCHEMBL31481300 | 0.70 | MEN1 (0.40) | MEN1KMT2ANPC1RAB9APAX8 | |
| SCHEMBL31481310 | 0.70 | MEN1 (0.46) | MEN1KMT2ANPC1RAB9APAX8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8372836-B2 | Spray dried formulation | BEND RESEARCH, INC. (US) | 2013-02-12 | — | — | US | disclosed |
| EP-1987030-B1 | 3 -DEAZAPURINE DERIVATIVES AS TLR7 MODULATORS | PFIZER LTD (GB) | 2011-11-09 | — | — | EP | disclosed |
| EP-2101741-B1 | SOLID DISPERSION COMPRISING A POORLY WATER SOLUBLE DRUG | BEND RES INC (US) | 2010-08-11 | — | — | EP | disclosed |
| US-7691877-B2 | Pharmaceuticals | PFIZER INC. (US) | 2010-04-06 | — | — | US | disclosed |
| US-20100029667-A1 | Spray dried formulation | BEND RESEARCH INC. | 2010-02-04 | — | — | US | disclosed |
| EP-2101741-A2 | SOLID DISPERSION COMPRISING A POORLY WATER SOLUBLE DRUG | BEND RESEARCH, INC. (US) | 2009-09-23 | — | — | EP | disclosed |
| EP-1987030-A1 | 3 -DEAZAPURINE DERIVATIVES AS TLR7 MODULATORS | Pfizer Limited (GB) | 2008-11-05 | — | — | EP | disclosed |
| WO-2008047201-A2 | SOLID DISPERSION COMPRISING A POORLY WATER SOLUBLE DRUG | PFIZER PRODUCTS INC. (US) | 2008-04-24 | — | — | WO | disclosed |
| WO-2007093901-A1 | 3 -DEAZAPURINE DERIVATIVES AS TLR7 MODULATORS | PFIZER LIMITED (GB) | 2007-08-23 | — | — | WO | disclosed |
| US-20070197478-A1 | NOVEL PHARMACEUTICALS | PFIZER LIMITED | 2007-08-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070197478-A1 | NOVEL PHARMACEUTICALS | TLR3, HAVCR2, TLR9 | MEN1 4459/4885KMT2A 4035/4885NPC1 785/4885 |
| US-20100029667-A1 | Spray dried formulation | PRKG1, PDE7A, PDE10A | MEN1 2145/4885KMT2A 4099/4885NPC1 592/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.