SCHEMBL2567919

SCHEMBL2567919

C=C(C)C(=O)N[C@@H](CCC(=O)OC)C(=O)O

nearest known ligand 0.59

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TGFBR1 P36897 2/20 0.59
FOLH1 Q04609 7/20 0.42
NAALAD2 Q9Y3Q0 2/20 0.42
RIMKLA Q8IXN7 1/20 0.42
SLC1A1 P43005 1/20 0.41
ALOX5 P09917 1/20 0.39
TSHR P16473 3/20 0.39
NOD1 Q9Y239 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2567915 0.87 ALOX5 (0.47) TGFBR1SLC1A1ALOX5TSHR
SCHEMBL8588109 0.84 TGFBR1 (0.53) TGFBR1FOLH1NAALAD2RIMKLANOD1
SCHEMBL1556929 0.84 TGFBR1 (0.65) TGFBR1FOLH1NAALAD2RIMKLA
SCHEMBL1556930 0.84 TGFBR1 (0.65) TGFBR1FOLH1NAALAD2RIMKLA
Ammonia Solution, Strong SCHEMBL18140383 0.83 TGFBR1 (0.62) TGFBR1FOLH1NAALAD2RIMKLA
Ammonia Solution, Strong SCHEMBL18140275 0.83 TGFBR1 (0.62) TGFBR1FOLH1NAALAD2RIMKLA
SCHEMBL17715158 0.82 MAPT (0.52) FOLH1NAALAD2RIMKLASLC1A1TSHR
SCHEMBL4577285 0.82 MAPT (0.52) FOLH1NAALAD2RIMKLASLC1A1TSHR
SCHEMBL8586350 0.82 TGFBR1 (0.50) TGFBR1FOLH1NAALAD2RIMKLANOD1
SCHEMBL8176290 0.81 TGFBR1 (0.61) TGFBR1FOLH1NAALAD2RIMKLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8313604-B2 Curable composition and temporary fixation method of member using it DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 2012-11-20 US disclosed
EP-1900761-B1 CURABLE COMPOSITION AND METHOD FOR TEMPORAL FIXATION OF STRUCTURAL MEMBER USING THE SAME DENKI KAGAKU KOGYO KK (JP) 2012-06-13 EP disclosed
EP-2383303-A1 Curable composition and temporary fixation method of member using it DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 2011-11-02 EP disclosed
CN-101213225-B Solidifying composition and method for temporary fixing of part by using the same DENKI KAGAKU KOGYO KK 2011-03-30 CN disclosed
US-20100012263-A1 CURABLE COMPOSITION AND METHOD FOR TEMPORAL FIXATION OF STRUCTURAL MEMBER USING THE SAME DENKI KAGAKU KOGYO KABUSHIKI KAISHA 2010-01-21 US disclosed
CN-101213225-A Solidifying composition and method for temporary fixing of part by using the same DENKI KAGAKU KOGYO KK (JP) 2008-07-02 CN disclosed
EP-1900761-A1 CURABLE COMPOSITION AND METHOD FOR TEMPORAL FIXATION OF STRUCTURAL MEMBER USING THE SAME DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 2008-03-19 EP disclosed