Sugi Predict

Sugi Predict / Compounds / SCHEMBL8176290

SCHEMBL8176290

SCHEMBL8176290

C=C(C)C(=O)NC(CCC(N)=O)C(=O)O

nearest known ligand 0.61

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ TGFBR1 P36897 2/20 0.61
▸ KMT2A Q03164 2/20 0.46
▸ CA2 P00918 5/20 0.43
▸ CA1 P00915 4/20 0.43
▸ FOLH1 Q04609 6/20 0.43
▸ NAALAD2 Q9Y3Q0 2/20 0.43
▸ RIMKLA Q8IXN7 1/20 0.43
▸ ALOX15 P16050 1/20 0.41
▸ BLM P54132 1/20 0.41
▸ PMP22 Q01453 1/20 0.41
▸ MMP2 P08253 2/20 0.38
▸ MMP9 P14780 2/20 0.38
▸ L3MBTL1 Q9Y468 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8176289 1.00 TGFBR1 (0.61) TGFBR1KMT2ACA2CA1FOLH1
SCHEMBL21585750 0.88 TGFBR1 (0.49) TGFBR1KMT2ACA2CA1FOLH1
SCHEMBL2969793 0.88 TGFBR1 (0.49) TGFBR1KMT2ACA2CA1FOLH1
SCHEMBL1556929 0.86 TGFBR1 (0.65) TGFBR1FOLH1NAALAD2RIMKLA
SCHEMBL2177297 0.86 KMT2A (0.48) TGFBR1KMT2ACA2CA1FOLH1
SCHEMBL1556930 0.86 TGFBR1 (0.65) TGFBR1FOLH1NAALAD2RIMKLA
SCHEMBL2177310 0.86 KMT2A (0.48) TGFBR1KMT2ACA2CA1FOLH1
Ammonia Solution, Strong SCHEMBL18140275 0.84 TGFBR1 (0.62) TGFBR1FOLH1NAALAD2RIMKLA
Ammonia Solution, Strong SCHEMBL18140383 0.84 TGFBR1 (0.62) TGFBR1FOLH1NAALAD2RIMKLA
SCHEMBL8176337 0.82 TGFBR1 (0.65) TGFBR1KMT2ACA2CA1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111542754-B Microcapsules for detecting and/or quantifying analytes in a sample 布林克公司 2025-03-11 — — CN claimed
CN-118510909-A Microsphere comprising a first material and a second material 布林克公司 2024-08-16 — — CN claimed
CN-114096514-A Amino acid based polymerizable compounds and ophthalmic devices made therefrom 强生视力健公司 2022-02-25 — — CN claimed
CN-107328684-B High-molecular electrostatic self-assembly sensing material for ion detection and preparation method and application thereof 常州大学 2020-05-26 — — CN claimed
EP-2938654-B1 MOLECULARLY IMPRINTED POLYMER OF SOL-GEL TYPE FOR SELECTIVELY TRAPPING ODOROUS MOLECULES OREAL (FR) 2016-08-24 — — EP claimed
US-20150342868-A1 MOLECULARLY IMPRINTED POLYMER OF SOL-GEL TYPE FOR SELECTIVELY TRAPPING ODOROUS MOLECULES LOREAL (FR) 2015-12-03 — — US claimed
US-20150320667-A1 MOLECULARLY IMPRINTED POLYMER FOR SELECTIVELY TRAPPING ODOROUS MOLECULES L'OREAL (FR) 2015-11-12 — — US claimed
EP-2938402-A1 MOLECULARLY IMPRINTED POLYMER FOR SELECTIVELY TRAPPING ODOROUS MOLECULES L'OREAL (FR) 2015-11-04 — — EP claimed
EP-2938654-A1 MOLECULARLY IMPRINTED POLYMER OF SOL-GEL TYPE FOR SELECTIVELY TRAPPING ODOROUS MOLECULES L'OREAL (FR) 2015-11-04 — — EP claimed
WO-2014102078-A1 MOLECULARLY IMPRINTED POLYMER OF SOL-GEL TYPE FOR SELECTIVELY TRAPPING ODOROUS MOLECULES L'OREAL (FR) 2014-07-03 — — WO claimed
WO-2014102077-A1 MOLECULARLY IMPRINTED POLYMER FOR SELECTIVELY TRAPPING ODOROUS MOLECULES L'OREAL (FR) 2014-07-03 — — WO claimed
CN-111542754-B Microcapsules for detecting and/or quantifying analytes in a sample 布林克公司 2025-03-11 — — CN disclosed
CN-118510909-A Microsphere comprising a first material and a second material 布林克公司 2024-08-16 — — CN disclosed
US-11246823-B2 Molecularly imprinted polymer of sol-gel type for selectively trapping odorous molecules L'OREAL (FR) 2022-02-15 — — US disclosed
WO-2021255552-A1 AMINO ACID-BASED POLYMERIZABLE COMPOUNDS AND OPHTHALMIC DEVICES PREPARED THEREFROM JOHNSON & JOHNSON VISION CARE, INC. (US) 2021-12-23 — — WO disclosed
WO-2014102078-A1 MOLECULARLY IMPRINTED POLYMER OF SOL-GEL TYPE FOR SELECTIVELY TRAPPING ODOROUS MOLECULES L'OREAL (FR) 2014-07-03 — — WO disclosed
WO-2014095427-A1 WATER-INSOLUBLE CYCLODEXTRIN POLYCONDENSATE; USES AS A CAPTURING AGENT L'OREAL (FR) 2014-06-26 — — WO disclosed
US-6046289-A FOR INHIBITING COAGULATION OF BLOOD PLATELETS, INHIBITING ADHESION OF ANIMAL CELLS, OR AS SUBSTRATE FOR CULTURING ANIMAL CELLS FUJIFILM CORPORATION (JP) 2000-04-04 — — US disclosed
EP-0488258-B1 Propenamide derivatives, polymers, copolymers and use thereof FUJI PHOTO FILM CO LTD (JP) 1996-04-17 — — EP disclosed
EP-0488258-A2 Propenamide derivatives, polymers, copolymers and use thereof FUJI PHOTO FILM CO., LTD. (JP) 1992-06-03 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11246823-B2 Molecularly imprinted polymer of sol-gel type for selectively trapping odorous molecules TAS2R30, TAS1R1, TAS2R10 TGFBR1 3206/4885KMT2A 3367/4885CA2 1996/4885
US-20150342868-A1 MOLECULARLY IMPRINTED POLYMER OF SOL-GEL TYPE FOR SELECTIVELY TRAPPING ODOROUS MOLECULES TAS2R30, TAS1R1, TAS2R10 TGFBR1 3206/4885KMT2A 3367/4885CA2 1996/4885
US-20150320667-A1 MOLECULARLY IMPRINTED POLYMER FOR SELECTIVELY TRAPPING ODOROUS MOLECULES OR10J3, OR51E2, MSMO1 TGFBR1 3102/4885KMT2A 3975/4885CA2 3230/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.