Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 5/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 5/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.37 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | RXRA | P19793 | 1/20 | 0.31 |
| ▸ | RXRB | P28702 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25684093 | 0.81 | CHRNB2 (0.37) | CHRNB2CHRNA4CHRNB4CHRNA3RAB9A | |
| SCHEMBL19756407 | 0.71 | IDO1 (0.32) | RXRARECQL | |
| SCHEMBL19251150 | 0.71 | FAAH (0.37) | RAB9ANPC1ACHE | |
| SCHEMBL19105520 | 0.69 | TYR (0.31) | — | |
| SCHEMBL19756422 | 0.68 | MAPT (0.39) | RAB9ANPC1 | |
| SCHEMBL18252824 | 0.67 | GABRA1 (0.32) | RAB9ANPC1 | |
| SCHEMBL19251360 | 0.66 | — | — | |
| SCHEMBL19756502 | 0.66 | HSD17B10 (0.32) | NPC1 | |
| SCHEMBL7694634 | 0.65 | PRSS1 (0.47) | CHRNB2CHRNA4CHRNB4CHRNA3RAB9A | |
| SCHEMBL11707907 | 0.65 | L3MBTL1 (0.42) | CHRNB2CHRNA4CHRM2CHRM4CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023114198-A2 | METHODS FOR THE SYNTHESIS OF COMPLEMENT FACTOR D INHIBITORS | ALEXION PHARMACEUTICALS, INC. (US) | 2023-06-22 | — | — | WO | disclosed |