Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 9/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25680341 | 0.82 | AKR1C3 (0.64) | AKR1C3ALDH1A1TSHRGAAHTT | |
| SCHEMBL20511063 | 0.80 | GAA (0.58) | AKR1C3ALDH1A1GAAMEN1KMT2A | |
| SCHEMBL3293780 | 0.79 | GAA (0.68) | AKR1C3ALDH1A1GAAHTTKMT2A | |
| SCHEMBL20510987 | 0.74 | ALDH1A1 (0.79) | ALDH1A1TSHRGAAHTTMEN1 | |
| SCHEMBL1928504 | 0.74 | GAA (0.67) | ALDH1A1GAAMEN1KMT2ALMNA | |
| SCHEMBL20511052 | 0.73 | GAA (1.00) | ALDH1A1TSHRGAAHTTMEN1 | |
| SCHEMBL10797158 | 0.73 | MAOB (0.72) | GAAKDM4E | |
| SCHEMBL28915156 | 0.72 | ALDH1A1 (0.72) | ALDH1A1TSHRMEN1KMT2ALMNA | |
| SCHEMBL25680418 | 0.72 | LMNA (0.77) | AKR1C3ALDH1A1TSHRGAALMNA | |
| SCHEMBL25680297 | 0.72 | LMNA (0.66) | AKR1C3ALDH1A1TSHRGAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230142508-A1 | COMPOUNDS AND METHODS FOR REGULATING INSULIN SECRETION | THE BROAD INSTITUTE, INC. (US) | 2023-05-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230142508-A1 | COMPOUNDS AND METHODS FOR REGULATING INSULIN SECRETION | IAPP, GPR119, PNLIP | AKR1C3 4220/4885ALDH1A1 4536/4885TSHR 264/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.