SCHEMBL25684237

SCHEMBL25684237

CCCc1ccc2c(c1)sc1cc3c(cc12)c1ccccc1n3C

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ HPGD P15428 5/20 0.46
▸ KDM4E B2RXH2 5/20 0.46
▸ ALDH1A1 P00352 4/20 0.46
▸ HSD17B10 Q99714 2/20 0.46
▸ MAPT P10636 5/20 0.43
▸ TSHR P16473 1/20 0.43
▸ RXRA P19793 1/20 0.42
▸ RXRB P28702 1/20 0.42
▸ GPR3 P46089 1/20 0.42
▸ KIF11 P52732 1/20 0.40
▸ MEN1 O00255 1/20 0.38
▸ HTT P42858 1/20 0.38
▸ KMT2A Q03164 1/20 0.38
▸ L3MBTL1 Q9Y468 1/20 0.38
▸ NPC1 O15118 1/20 0.38
▸ LMNA P02545 1/20 0.38
▸ RAB9A P51151 1/20 0.38
▸ NPSR1 Q6W5P4 1/20 0.38
▸ PABPC1 P11940 1/20 0.38
▸ GFER P55789 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25683676 0.95 HPGD (0.46) HPGDKDM4EALDH1A1HSD17B10MAPT
SCHEMBL25682708 0.94 KDM4E (0.43) HPGDKDM4EALDH1A1HSD17B10MAPT
SCHEMBL25684155 0.94 HPGD (0.45) HPGDKDM4EALDH1A1HSD17B10MAPT
SCHEMBL25684233 0.92 KDM4E (0.43) HPGDKDM4EALDH1A1HSD17B10MAPT
SCHEMBL25998067 0.90 RORA (0.40) HPGDKDM4EALDH1A1HSD17B10MAPT
SCHEMBL25682510 0.89 KDM4E (0.43) HPGDKDM4EALDH1A1HSD17B10MAPT
SCHEMBL25683583 0.88 HPGD (0.45) HPGDKDM4EALDH1A1HSD17B10MAPT
SCHEMBL24667920 0.87 RXRA (0.46) HPGDKDM4EALDH1A1HSD17B10MAPT
SCHEMBL25683678 0.87 KDM4E (0.43) HPGDKDM4EALDH1A1HSD17B10MAPT
SCHEMBL25683586 0.84 RORA (0.40) HPGDKDM4EALDH1A1HSD17B10MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230265106-A1 COMPOUND, LIGHT-EMITTING MATERIAL, AND LIGHT-EMITTING ELEMENT KYULUX, INC. (JP) 2023-08-24 — — US disclosed
EP-4190791-A1 COMPOUND, LIGHT-EMITTING MATERIAL, AND LIGHT-EMITTING ELEMENT Kyulux, Inc. (JP) 2023-06-07 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230265106-A1 COMPOUND, LIGHT-EMITTING MATERIAL, AND LIGHT-EMITTING ELEMENT CRY1, CCNE2, CRY2 HPGD 1840/4885KDM4E 1997/4885ALDH1A1 603/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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