Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | SPHK1 | Q9NYA1 | 10/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.45 |
| ▸ | SIRT2 | Q8IXJ6 | 5/20 | 0.44 |
| ▸ | SIRT1 | Q96EB6 | 3/20 | 0.44 |
| ▸ | SIRT3 | Q9NTG7 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22299573 | 0.83 | HSD17B10 (0.44) | HSD17B10CA1CA2CA7CA14 | |
| SCHEMBL29323297 | 0.82 | SPHK1 (0.54) | HSD17B10SPHK1CA1CA2CA7 | |
| SCHEMBL21298844 | 0.78 | LTA4H (0.60) | SPHK1 | |
| SCHEMBL20283600 | 0.77 | KMT2A (0.46) | — | |
| SCHEMBL20353846 | 0.76 | HDAC8 (0.58) | HSD17B10TSHR | |
| SCHEMBL11515231 | 0.76 | HDAC8 (0.58) | HSD17B10TSHR | |
| SCHEMBL21875528 | 0.76 | HSD17B10 (0.46) | HSD17B10SPHK1CA1CA2CA7 | |
| SCHEMBL17027832 | 0.76 | ALDH1A1 (0.46) | CA1CA2SIRT2SIRT1 | |
| SCHEMBL17027708 | 0.76 | ALDH1A1 (0.46) | CA1CA2SIRT2SIRT1 | |
| SCHEMBL17027725 | 0.76 | ALDH1A1 (0.46) | CA1CA2SIRT2SIRT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4201431-A1 | INTERMEDIATE FOR PREPARING ANTIBODY-DRUG CONJUGATE (ADC), PREPARATION METHOD THEREFOR, AND USE THEREOF | Dartsbio Pharmaceuticals Ltd. (CN) | 2023-06-28 | — | — | EP | disclosed |