SCHEMBL25690657

SCHEMBL25690657

Cl[Si@H](c1ccccc1)c1ccc(-c2ccccc2)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.48
ALDH1A1 P00352 2/20 0.47
TAAR1 Q96RJ0 3/20 0.42
MAPK1 P28482 1/20 0.42
CYP3A4 P08684 1/20 0.42
HSD17B10 Q99714 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
MMP3 P08254 1/20 0.42
BCL2L1 Q07817 1/20 0.42
CA1 P00915 2/20 0.37
CA2 P00918 2/20 0.37
MGLL Q99685 1/20 0.37
KIF11 P52732 1/20 0.37
ESR2 Q92731 1/20 0.37
NOTUM Q6P988 1/20 0.36
ALOX5 P09917 1/20 0.36
CYP1A1 P04798 1/20 0.34
CYP1B1 Q16678 1/20 0.34
CA12 O43570 1/20 0.34
CA9 Q16790 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL297217 0.86 TSHR (0.39) CYP1A2ALDH1A1HSD17B10TDP1CA1
Water SCHEMBL9174447 0.83 TSHR (0.37) CYP1A2ALDH1A1TDP1CA1CA2
SCHEMBL22830125 0.83 TSHR (0.37) CYP1A2ALDH1A1TDP1CA1CA2
SCHEMBL28753733 0.78 ALDH1A1 (0.53) CYP1A2ALDH1A1TAAR1MAPK1CYP3A4
SCHEMBL3482541 0.77 ACHE (0.48) ALDH1A1TDP1CA1CA2CA12
Biphenyl SCHEMBL7582303 0.76 ALDH1A1 (0.69) CYP1A2ALDH1A1TAAR1MAPK1CYP3A4
SCHEMBL24409173 0.75 ALDH1A1 (0.47) CYP1A2ALDH1A1TAAR1MAPK1CYP3A4
SCHEMBL15987409 0.75 ALDH1A1 (0.56) CYP1A2ALDH1A1TAAR1MAPK1CYP3A4
Tannin Pyrogallol SCHEMBL21448 0.72 ALDH1A1 (0.90) CYP1A2ALDH1A1TAAR1MAPK1CYP3A4
SCHEMBL827097 0.72 ALDH1A1 (0.90) CYP1A2ALDH1A1TAAR1MAPK1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230189634-A1 LIGHT EMITTING ELEMENT AND POLYCYCLIC COMPOUND FOR THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2023-06-15 US disclosed