Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 6/20 | 0.47 |
| ▸ | CHRNA4 | P43681 | 6/20 | 0.47 |
| ▸ | CHRNB4 | P30926 | 4/20 | 0.47 |
| ▸ | CHRNA3 | P32297 | 4/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | GUCY1B2 | O75343 | 2/20 | 0.44 |
| ▸ | GUCY1A2 | P33402 | 2/20 | 0.44 |
| ▸ | GUCY1A1 | Q02108 | 2/20 | 0.44 |
| ▸ | GUCY1B1 | Q02153 | 2/20 | 0.44 |
| ▸ | USP30 | Q70CQ3 | 5/20 | 0.41 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.41 |
| ▸ | CD38 | P28907 | 1/20 | 0.40 |
| ▸ | SSTR4 | P31391 | 3/20 | 0.40 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25690442 | 1.00 | CHRNB2 (0.47) | CHRNB2CHRNA4CHRNB4CHRNA3HDAC4 | |
| SCHEMBL25690692 | 1.00 | CHRNB2 (0.47) | CHRNB2CHRNA4CHRNB4CHRNA3HDAC4 | |
| SCHEMBL25690440 | 0.92 | CHRNB2 (0.45) | CHRNB2CHRNA4CHRNB4CHRNA3HDAC4 | |
| SCHEMBL25690436 | 0.90 | ALDH1A1 (0.39) | CHRNB2CHRNA4CHRNB4CHRNA3USP30 | |
| SCHEMBL25696652 | 0.87 | CHRNB2 (0.48) | CHRNB2CHRNA4CHRNB4CHRNA3HDAC4 | |
| SCHEMBL25690421 | 0.84 | DPP4 (0.45) | CD38ALDH1A1 | |
| SCHEMBL25690689 | 0.79 | CD38 (0.48) | CD38 | |
| SCHEMBL25690429 | 0.78 | CNR2 (0.48) | HDAC4HDAC6 | |
| SCHEMBL25690437 | 0.78 | CHRM5 (0.40) | ALDH1A1 | |
| SCHEMBL25690606 | 0.78 | GRM5 (0.38) | CD38ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023122140-A1 | PARP1 INHIBITORS | SYNNOVATION THERAPEUTICS, INC. (US) | 2023-06-29 | — | — | WO | disclosed |